Kidney function, albuminuria and life expectancy

Canadian Journal of Kidney Health and Disease
Tanvir C TurinBrenda R Hemmelgarn

Abstract

Lower estimated glomerular filtration rate is associated with reduced life expectancy. Whether this association is modified by the presence or absence of albuminuria, another cardinal finding of chronic kidney disease, is unknown. Our objective was to estimate the life expectancy of middle-aged men and women with varying levels of eGFR and concomitant albuminuria. A retrospective cohort study. A large population-based cohort identified from the provincial laboratory registry in Alberta, Canada. Adults aged ≥30 years who had outpatient measures of serum creatinine and albuminuria between May 1, 2002 and March 31, 2008. Baseline levels of kidney function identified from serum creatinine and albuminuria measurements. all cause mortality during the follow-up. Patients were categorized based on their estimated glomerular filtration rate (eGFR) (≥60, 45-59, 30-44, and 15-29 mL/min/1 · 73 m(2)) as well as albuminuria (normal, mild, and heavy) measured by albumin-to-creatinine ratio or urine dipstick. The abridged life table method was applied to calculate the life expectancies of men and women from age 40 to 80 years across combined eGFR and albuminuria categories. We also categorized participants by severity of kidney disease (low ri...Continue Reading

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Citations

Feb 6, 2020·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Veridiana AndrioliWilson Aguiar
Oct 5, 2017·Journal of Nephropathology·Rotimi OluyomboAdewale Akinsola
Oct 5, 2016·Psychological Science in the Public Interest : a Journal of the American Psychological Society·Daniel J SimonsElizabeth A L Stine-Morrow
Feb 20, 2018·Current Diabetes Reports·O Kenrik DuruKeith Norris
Dec 29, 2020·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Peter RossingChristiane Otto
Nov 5, 2019·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Robert M ShavelleLynne Turner-Stokes

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