PMID: 3881478Jan 1, 1985

Killing of Escherichia coli by human polymorphonuclear leucocytes in the presence of Bacteroides fragilis

Journal of Clinical Pathology
W A VelD M MacLaren


The inhibitory effect of Bacteroides fragilis on the in vitro killing of Escherichia coli by polymorphonuclear leucocytes was studied with two pairs of E coli and B fragilis isolated from human wound infections. Both B fragilis strains behaved similarly: they inhibited the killing of one E coli strain, while the killing of the other E coli strain was not affected. The different behaviour of the two E coli strains depended on their need for fresh serum in the killing by the polymorphonuclear leucocytes. The inhibitory effect of the B fragilis strains could be completely accounted for by their effect on complement.


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Related Concepts

Bacteroides fragilis
Blood Bactericidal Activity
Hemolytic Complement
Alkalescens-Dispar Group
Neutrophil Band Cells
Surgical Wound Infection

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