PMID: 2493134Mar 1, 1989Paper

KIN, a mammalian nuclear protein immunologically related to E. coli RecA protein

Mutation Research
Jaime F AnguloR Devoret

Abstract

A polypeptide of about 120 kDa, called KIN, has been identified in rat FR 3T3 cells by immunoblotting using affinity-purified antibodies against the RecA protein of Escherichia coli (38 kDa). The KIN protein as shown by fluorescent light microscopy and electron microscopy is essentially concentrated in the nucleus. Its level is higher in proliferating than in quiescent cells. Cell treatment with mitomycin C increases the level of the KIN protein. We sought similar proteins in other mammalian cells. Proteins with the same electrophoretic mobility were detected in mouse, monkey and human cell lines as well as in rat and mouse embryos.

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Citations

Apr 25, 2000·Molecular and Cellular Biology·C BlattnerP Herrlich
May 30, 2007·Dental Clinics of North America·Raymond L Bertolotti
Mar 7, 2002·The Journal of Biological Chemistry·Denis S F BiardJaime F Angulo
Jan 1, 1990·Critical Reviews in Biochemistry and Molecular Biology·A I Roca, M M Cox
May 1, 1993·Molecular & General Genetics : MGG·S SommerR Devoret
Jul 17, 2019·European Biophysics Journal : EBJ·José Renato Pattaro JúniorFlávio Augusto Vicente Seixas
Aug 22, 2021·Biomolecular NMR Assignments·Isabella Otenio de LourençoÍcaro Putinhon Caruso
Aug 28, 2021·Current Issues in Molecular Biology·Vanessa Pinatto GasparMaria Aparecida Fernandez

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