Kindling of claustrum and insular cortex: comparison to perirhinal cortex in the rat

The European Journal of Neuroscience
P MohapelM E Corcoran

Abstract

The perirhinal cortex has recently been implicated in the kindling of limbic generalized seizures. The following experiments in rats tested the selectivity of the perirhinal cortex's epileptogenic properties by comparing its kindling profile with those of the adjacent insular cortex, posterior (dorsolateral) claustrum and amygdala. The first experiment examined the kindling and EEG profiles, and found that both the claustrum and insular cortex demonstrated rapid epileptogenic properties similar to the perirhinal cortex, including very rapid kindling rates and short latencies to convulsion. Furthermore, electrical stimulation of all three structures led to a two-phase progression through stage-5 seizures which had characteristics of both neocortical and amygdaloid kindling. In a second experiment rats were suspended in a harness to allow for more detailed documentation of both forelimb and hindlimb convulsions. With this procedure we were able to detect subtle yet unique differences in convulsion characteristics from each of the kindled sites and stage-5 seizure phases. Some of these convulsive parameters were correlated with changes in FosB/DeltaFosB protein and BDNF mRNA expression measured two hours after the last convulsion....Continue Reading

References

Jan 1, 1975·Electroencephalography and Clinical Neurophysiology·R J Racine
Nov 1, 1975·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·W M Burnham
Dec 15, 1992·The Journal of Comparative Neurology·F ClascáF Reinoso-Suárez
Jan 1, 1992·Canadian Journal of Physiology and Pharmacology·R A Swanson
Aug 1, 1991·Brain Research. Molecular Brain Research·G C TeskeyD P Cain
Feb 12, 1990·Behavioural Brain Research·G FouriezosW Pagotto
Nov 1, 1988·Experimental Neurology·M DragunowG S Robertson
Oct 1, 1986·Physiology & Behavior·J P Kroon, A L Riley
Oct 22, 1986·Brain Research·W T Seidel, M E Corcoran
Mar 1, 1972·Electroencephalography and Clinical Neurophysiology·R J Racine
Jun 27, 1983·Brain Research·I M Altman, M E Corcoran
Oct 20, 1983·The Journal of Comparative Neurology·T W DeaconK W Eckmann
Sep 1, 1995·Trends in Pharmacological Sciences·K R PennypackerM K McMillian
Jun 25, 1993·Brain Research·D C McIntyreJ N Armstrong
Oct 1, 1996·Experimental Neurology·L ChenW M Burnham
Dec 1, 1996·Epilepsy Research·M E Kelly, D C McIntyre
Dec 1, 1996·Progress in Neurobiology·W Löscher, U Ebert
Aug 1, 1997·Electroencephalography and Clinical Neurophysiology·J A Wada, T Kudo
Jul 24, 1998·Brain Research. Molecular Brain Research·B J ChiassonH A Robertson
Dec 22, 1998·Brain, Behavior and Evolution·P KowiańskiJ Moryś
Sep 22, 2000·Epilepsia·P MohapelM E Corcoran

❮ Previous
Next ❯

Citations

Mar 31, 2004·Neuroscience·A H SheerinM E Corcoran
May 28, 2008·Epilepsia·Dan C McIntyre, Krista L Gilby
Dec 17, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Jared B Smith, Kevin D Alloway
Nov 24, 2004·The Journal of Comparative Neurology·José Carlos DávilaSalvador Guirado
Jun 19, 2010·Neuroscience Letters·Ozlem AkmanFiliz Yilmaz Onat
Jul 5, 2008·Brain Research Bulletin·Przemysław KowiańskiJanusz Moryś
Nov 12, 2015·Frontiers in Behavioral Neuroscience·Maciej M Jankowski, Shane M O'Mara
Sep 4, 2015·The Journal of Physiological Sciences : JPS·Rena Orman
Dec 7, 2007·The European Journal of Neuroscience·Jessica R Sudbury, Massimo Avoli
May 26, 2010·The European Journal of Neuroscience·Aleksandra BortelMassimo Avoli
Jun 15, 2004·Progress in Neurobiology·Kiyoshi MorimotoRonald J Racine
Oct 6, 2005·Neuroscience·T MiyashitaK S Rockland
Aug 22, 2013·Autonomic Neuroscience : Basic & Clinical·Masoumeh HatamAli Nasimi
Dec 30, 2014·Frontiers in Neurology·David N Vaughan, Graeme D Jackson
Nov 27, 2014·Frontiers in Neuroinformatics·Carinna M Torgerson, John D Van Horn
Jan 27, 2016·Polish Journal of Veterinary Sciences·R SzalakM B Arciszewski
Aug 2, 2013·Experimental Animals·Ryoko HashimotoTakashi Kuramoto
Feb 28, 2019·Frontiers in Neuroanatomy·Lalitha KuradaMohamad Z Koubeissi

❮ Previous
Next ❯

Related Concepts

Related Feeds

Amygdala and Midbrain Dopamine

The midbrain dopamine system is widely studied for its involvement in emotional and motivational behavior. Some of these neurons receive information from the amygdala and project throughout the cortex. When the circuit and transmission of dopamine is disrupted symptoms may present. Here is the latest research on the amygdala and midbrain dopamine.

Amygdala: Sensory Processes

Amygdalae, nuclei clusters located in the temporal lobe of the brain, play a role in memory, emotional responses, and decision-making. Here is the latest research on sensory processes in the amygdala.