Kinesin Motor Enzymology: Chemistry, Structure, and Physics of Nanoscale Molecular Machines

Biophysics Reviews
J C Cochran

Abstract

Molecular motors are enzymes that convert chemical potential energy into controlled kinetic energy for mechanical work inside cells. Understanding the biophysics of these motors is essential for appreciating life as well as apprehending diseases that arise from motor malfunction. This review focuses on kinesin motor enzymology with special emphasis on the literature that reports the chemistry, structure and physics of several different kinesin superfamily members.

References

Apr 29, 1992·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·R S GoodyA Wittinghofer
Nov 9, 1989·Nature·J HowardR D Vale
Mar 1, 1989·The Biochemical Journal·C T Zimmerle, C Frieden
Sep 1, 1988·Proceedings of the National Academy of Sciences of the United States of America·D D Hackney
Dec 1, 1986·Proceedings of the National Academy of Sciences of the United States of America·E R HenryR M Hochstrasser
Mar 1, 1969·Biochemistry·B Finlayson, E W Taylor
Nov 1, 1971·Archives of Biochemistry and Biophysics·K Shikama
Apr 5, 1966·Journal of the American Chemical Society·D L Miller, F H Westheimer
Apr 5, 1966·Journal of the American Chemical Society·D L Miller, F H Westheimer
Jan 1, 1995·Cell Motility and the Cytoskeleton·S RayK H Downing
Feb 23, 1995·Nature·S P GilbertK A Johnson
Jun 1, 1993·The Journal of Cell Biology·S RayJ Howard
Jun 3, 1994·Cell·K Svoboda, S M Block
Sep 3, 1996·Proceedings of the National Academy of Sciences of the United States of America·K HiroseL A Amos
Oct 1, 1996·Current Biology : CB·I ArnalR H Wade
Jan 10, 1997·The Journal of Biological Chemistry·Y Z Ma, E W Taylor
Mar 21, 1997·The Journal of Biological Chemistry·W JiangD D Hackney
Jul 24, 1997·Nature·M J Schnitzer, S M Block
Jul 24, 1997·Nature·W HuaJ Gelles
Jul 25, 1997·Cell·G WoehlkeR D Vale
Sep 4, 1997·Nature·U Henningsen, M Schliwa
Nov 1, 1995·Chemistry & Biology·S J Admiraal, D Herschlag
Jan 10, 1998·The Journal of Biological Chemistry·E Pechatnikova, E W Taylor
Jan 24, 1998·Biochemistry·S SackE Mandelkow
Jan 1, 1997·Annual Review of Cell and Developmental Biology·R D Vale, R J Fletterick
Feb 10, 1998·Biochemistry·S P GilbertK A Johnson
Feb 10, 1998·Biochemistry·M L MoyerK A Johnson

❮ Previous
Next ❯

Citations

Jan 21, 2018·The Journal of Cell Biology·Yang YueKristen J Verhey
Feb 6, 2018·Cellular and Molecular Life Sciences : CMLS·Sudhir Kumar SinghLarisa Gheber
Nov 8, 2017·ELife·Wonmuk HwangMartin Karplus
Mar 29, 2019·Soft Matter·Linnea M LemmaZvonimir Dogic
Sep 12, 2019·Proceedings of the National Academy of Sciences of the United States of America·Wonmuk Hwang, Martin Karplus
Jun 17, 2018·Physical Review. E·Gert Knoops, Carlo Vanderzande
Jul 14, 2017·The Journal of Biological Chemistry·Kayla M BellJared C Cochran
Jul 19, 2018·Current Biology : CB·Pan WangWeihong Qiu
Mar 30, 2021·The European Physical Journal. E, Soft Matter·Adam R LamsonMeredith D Betterton
Jun 4, 2020·Biophysical Journal·Lavi S Bigman, Yaakov Levy
Jul 3, 2021·International Journal of Molecular Sciences·Himanshu PandeyLarisa Gheber
Jul 19, 2021·Cellular and Molecular Life Sciences : CMLS·Himanshu PandeyLarisa Gheber
Sep 23, 2020·Organic Letters·Isuru M JayalathC Scott Hartley

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Schweizerische medizinische Wochenschrift
P Christen
Methods in Enzymology
Yoshiharu IshiiToshio Yanagida
Nature
Justin E Molloy, Stephan Schmitz
© 2022 Meta ULC. All rights reserved