PMID: 15333701Aug 31, 2004Paper

Kinetic parameters and plasma zinc concentration correlate well with net loss and gain of zinc from men

The Journal of Nutrition
N M LoweJanet King

Abstract

The search for a reliable, convenient indicator of Zn status was the focus of research for several decades. Plasma Zn concentration is still the most widely used clinical measurement, despite the known problems of interpretation. More recently, researchers suggested that isotopically determined kinetic parameters, such as the exchangeable Zn pool (EZP), may more accurately and reliably reflect body Zn status. The objective of this study was to examine the relationship between net body Zn loss and gain during acute changes in dietary Zn intake with biochemical and kinetic indices of Zn status. Five men participated in an 85-d Zn depletion/repletion study. Net body Zn loss and gain were determined from the difference between dietary plus intravenously administered Zn and Zn excretion. Biochemical indicators of Zn status included plasma Zn, plasma alkaline phosphatase activity, and plasma retinol binding protein concentration. Following intravenous administration of (70)Zn or (67)Zn, a compartmental model was used to determine EZP mass, fractional Zn absorption, endogenous zinc excretion (EZE), and plasma Zn flux. The changes in total body zinc correlated best with changes in plasma Zn (r(2) = 0.826, P < 0.001), EZE (r(2) = 0.773,...Continue Reading

References

Oct 1, 1978·Annals of Internal Medicine·A S PrasadM R Fox
Nov 1, 1990·The Journal of Nutrition·J C King
Jun 1, 1985·The American Journal of Clinical Nutrition·K Weismann, H Høyer
Dec 1, 1972·Pediatric Research·K M HambidgeJ D Baum
Mar 1, 1970·The American Journal of Clinical Nutrition·L M Klevay
Aug 1, 1983·The American Journal of Clinical Nutrition·D B MilneH H Sandstead
Mar 1, 1996·The American Journal of Clinical Nutrition·L SianK M Hambidge
Jun 1, 1997·The American Journal of Clinical Nutrition·N M LoweJ C King
Aug 13, 1998·The American Journal of Clinical Nutrition·P Christian, K P West
Jul 14, 2001·The American Journal of Clinical Nutrition·J C KingM J Jackson

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Citations

May 13, 2008·The American Journal of Clinical Nutrition·Valentin KiedaischFlorian Lang
May 8, 2009·The American Journal of Clinical Nutrition·Nicola M LoweTamás Decsi
Jan 17, 2012·Journal of Burn Care & Research : Official Publication of the American Burn Association·Nancy Caldis-CoutrisSarvesh Logsetty
May 22, 2013·Journal of Pediatric Gastroenterology and Nutrition·K Ryan WessellsKenneth H Brown
Apr 18, 2014·Nutrition Reviews·Silvia Bel-SerratUNKNOWN EURRECA Network
Mar 11, 2016·The Journal of Nutrition·Janet C KingDaniel J Raiten
May 10, 2006·Eating and Weight Disorders : EWD·C Laird BirminghamM Gao
Jan 9, 2007·The American Journal of Clinical Nutrition·Linda J HarveySusan J Fairweather-Tait
Nov 9, 2007·Food and Nutrition Bulletin·Christa L Fischer Walker, Robert E Black
Oct 25, 2008·The British Journal of Nutrition·Stefan PilzWinfried März
Aug 2, 2008·JPEN. Journal of Parenteral and Enteral Nutrition·Daren K HeylandHector Wong
Aug 21, 2009·Journal of Veterinary Emergency and Critical Care·Julia E Cummings, Jan P Kovacic
Jul 5, 2008·The British Journal of Nutrition·Rosalind S GibsonKenneth H Brown
Jun 4, 2015·Arquivos De Gastroenterologia·Camila Bitu Moreno BragaSelma Freire de Carvalho da Cunha
Dec 13, 2006·The American Journal of Clinical Nutrition·Nancy F KrebsK Michael Hambidge
Nov 9, 2007·Food and Nutrition Bulletin·Sonja Y HessKenneth H Brown
Jul 9, 2005·The American Journal of Clinical Nutrition·Christine Feillet-CoudrayCharles Coudray
Feb 24, 2015·JPEN. Journal of Parenteral and Enteral Nutrition·Natalie Z CvijanovichHector R Wong
Nov 6, 2014·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Juna V KonomiLou Ann S Brown
Mar 17, 2015·PloS One·Marc F HoylaertsJosé Luis Millán
Jul 23, 2015·The British Journal of Nutrition·Miriam M J van RietGeert P J Janssens
Jul 4, 2006·Indian Journal of Pediatrics·Abdullah H BaquiLaura E Caulfield
Aug 26, 2011·The American Journal of Clinical Nutrition·Manuel RuzNancy F Krebs
Jul 1, 2011·The American Journal of Clinical Nutrition·Janet C King
Feb 4, 2006·Journal of Pediatric Gastroenterology and Nutrition·Nancy F KrebsK Michael Hambidge

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