Kinetic regulation of vesicle endocytosis at synapses

Trends in Neurosciences
Ling-Gang Wu

Abstract

Studies from a variety of synapses indicate that the time course of endocytosis ranges from less than a second to hundreds of seconds. This raises questions about how the time course of endocytosis is regulated and why different rates of endocytosis are needed. Recent progress sheds light on these issues. Neuronal firing frequency and duration determine the time course of endocytosis. The dynamic nature of this time course could be a result of multiple endocytic pathways and/or of regulation by a variety of modulators. Because endocytosis is crucial for maintaining transmitter release during repetitive stimulation, regulation of endocytosis could thus provide a mechanism by which synaptic plasticity is achieved.

References

Dec 1, 1989·Quarterly Journal of Experimental Physiology : an International Journal of the Physiological Society·J E Heuser
May 1, 1973·The Journal of Cell Biology·B CeccarelliA Mauro
Dec 18, 1981·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·J Meldolesi, B Ceccarelli
Aug 29, 1995·Proceedings of the National Academy of Sciences of the United States of America·C R ArtalejoH C Palfrey
Oct 6, 1994·Nature·R HeidelbergerG Matthews
Jul 15, 1996·The Journal of Physiology·S F Hsu, M B Jackson
Nov 1, 1996·The Journal of Cell Biology·J H Koenig, K Ikeda
Jul 1, 1997·Trends in Neurosciences·J K Angleson, W J Betz
Apr 29, 1998·Annual Review of Physiology·W J Betz, J K Angleson
Apr 15, 1999·Annual Review of Neuroscience·A J CochillaW J Betz
Jan 19, 2000·Proceedings of the National Academy of Sciences of the United States of America·T Moser, D Beutner
Aug 11, 2000·Science·J H BollmannJ G Borst
Oct 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·C F Stevens, J H Williams
Feb 15, 2001·Nature Neuroscience·S Sankaranarayanan, T A Ryan
Oct 12, 2001·Current Opinion in Neurobiology·T A Ryan
Oct 24, 2001·Trends in Neurosciences·M A Cousin, P J Robinson
Oct 25, 2001·Proceedings of the National Academy of Sciences of the United States of America·N HarataR W Tsien
Dec 6, 2001·Proceedings of the National Academy of Sciences of the United States of America·G NevesL Lagnado
Apr 18, 2002·Proceedings of the National Academy of Sciences of the United States of America·Cristina R ArtalejoH Clive Palfrey
Jun 6, 2003·Nature·Sunil P Gandhi, Charles F Stevens
Jun 20, 2003·Proceedings of the National Academy of Sciences of the United States of America·Stefan HallermannManfred Heckmann
Aug 5, 2003·Neuron·David A RichardsWilliam J Betz
Aug 12, 2003·Nature Neuroscience·Kristina D MichevaStephen J Smith
Aug 14, 2003·Biochimica Et Biophysica Acta·Manfred Lindau, Guillermo Alvarez de Toledo

❮ Previous
Next ❯

Citations

Sep 28, 2006·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Ray TruantRandy Singh Atwal
Jan 7, 2005·Molecular Biology of the Cell·Christopher L BrettRajini Rao
Dec 16, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Wei WuLing-Gang Wu
Sep 4, 2008·Visual Neuroscience·Qun-Fang WanRuth Heidelberger
Sep 4, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Xin-Sheng Wu, Ling-Gang Wu
Sep 3, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Tao SunLing-Gang Wu
Jan 12, 2007·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Ray TruantAnjee Burtnik
Sep 21, 2012·Molecular Neurobiology·Raquel CanoLucía Tabares
Apr 30, 2005·The Journal of Physiology·Haibing Teng, Robert S Wilkinson
Aug 10, 2007·The European Journal of Neuroscience·Rajesh KhannaElise F Stanley
Jul 19, 2005·Journal of Molecular Biology·Winfried Weissenhorn
Nov 13, 2009·Communicative & Integrative Biology·Yongling ZhuStephen F Heinemann
Nov 11, 2006·Nephron. Physiology·Andrew M Hall, Robert J Unwin
Nov 18, 2008·The Journal of Biological Chemistry·Wenbo LuSumiko Mochida
May 21, 2013·The Journal of Biological Chemistry·Shota TanifujiSumiko Mochida
May 17, 2005·The Journal of Biological Chemistry·Zoya MarinovaGeorgy Bakalkin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.