Kinetics and modeling of degradation of ionophore antibiotics by UV and UV/H2O2
Abstract
Ionophore antibiotics (IPAs), one of the major groups of pharmaceuticals used in livestock industry, have been found to contaminate agricultural runoff and surface waters via land application of animal manures as fertilizers. However, limited research has investigated the means to remove IPAs from water sources. This study investigates the degradation of IPAs by using ultraviolet (UV) photolysis and UV combined with hydrogen peroxide (UV/H2O2) advanced oxidation process (AOP) under low-pressure (LP) UV lamps in various water matrices. Three widely used (monensin, salinomycin, and narasin) and one model (nigericin) IPAs exhibit low light absorption in the UV range and degrade slowly at the light intensity of 3.36 × 10(-6) Einstein·L(-1)·s(-1) under UV photolysis conditions. However, IPAs react with hydroxyl radicals produced by UV/H2O2 at fast reaction rates, with second-order reaction rate constants at (3.49-4.00) × 10(9) M(-1)·s(-1). Water matrix constituents enhanced the removal of IPAs by UV photolysis but inhibited UV/H2O2 process. A steady-state kinetic model successfully predicts the impact of water constituents on IPA degradation by UV/H2O2 and determines the optimal H2O2 dose by considering both energy consumption and I...Continue Reading
References
Citations
Photo-degradation ibuprofen by UV/H2 O2 process: response surface analysis and degradation mechanism
Related Concepts
Related Feeds
Antifungals
An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.
Antifungals (ASM)
An antifungal, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis, cryptococcal meningitis, and others. Discover the latest research on antifungals here.