Kinetics and tissue repair process following fractional bipolar radiofrequency treatment

Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology
G KokolakisM A Hofmann

Abstract

Fractionated radiofrequency (RF) tissue tightening is an alternative method to fractionated laser treatment of skin wrinkling, laxity and acne scars, with reduced risk of scarring or persistent pigmentation. The aim of this study was to evaluate and quantify the wound healing process after RF treatment. 12 patients were treated with a 64-pin fractional bipolar RF device with 60 mJ/pin applied energy. Confocal laser scanning microscopy (CLSM) examination was performed on day 1, day 2, day 7 and day 14 after treatment. Clinical wound healing process was measured and expressed as a percentage. All patients developed erythema, mild edema and crusts at the treated areas. Two weeks after treatment clinical symptoms resolved. During ablation patients reported moderate pain. Directly after ablation microscopic ablation zones could be detected in CLSM. Measurement of MAZ at epidermis, dermo-epidermal junction and papilary dermis showed a constant diameter until two weeks after treatment. Re-epithelization of the MAZ could be detected already 1 week after treatment. However, 2 weeks after ablation the honeycomb pattern of the epidermis was not yet completely restored. Bipolar fractionated RF treatment demonstrates clinically a rapid woun...Continue Reading

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Citations

Jan 17, 2020·Lasers in Surgery and Medicine·Georgios KokolakisMaja A Hofmann
Nov 21, 2021·Scientific Reports·Mina Ghanbari, Ghader Rezazadeh

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