Kinetics of lymphocyte subpopulations and their functions in cases of amoebic liver abscess

Transactions of the Royal Society of Tropical Medicine and Hygiene
N K GangulyA Koshy

Abstract

This study shows the relationship between lymphocyte subpopulations and their response to non-specific stimulant phytohaemagglutinin (PHA) and specific stimulant (amoebic antigen) in cases of amoebic liver abscess in relation to the duration of disease, based on the first appearance of symptoms and/or signs, 26 patients with amoebic liver abscess and 20 normal, healthy controls were studied. Five of the patients gave a history of alcohol intake for the last 10 to 15 years. Eight had a solitary abscess and five had multiple abscesses, as seen on liver scan. No change in the B cell count was noticed in any of the patients. Depression of the T cell number and function was noticed from two weeks onwards. A history of alcohol intake made no difference. Cases with multiple liver abscesses were more immunologically depressed than were those with a solitary abscess.

References

Mar 20, 1976·Lancet·R C MahajanD V Datta
Nov 1, 1973·The American Journal of Tropical Medicine and Hygiene·T SavanatN Nimitmongkol
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·M de S Wijesundera
Jan 1, 1980·Transactions of the Royal Society of Tropical Medicine and Hygiene·R C Mahajan, N K Ganguly
Dec 1, 1954·Annals of Tropical Medicine and Parasitology·B G MAEGRAITH, C HARINASUTA

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Citations

Jan 1, 1985·Transactions of the Royal Society of Tropical Medicine and Hygiene·N J GillR C Mahajan
Jan 1, 1985·Transactions of the Royal Society of Tropical Medicine and Hygiene·A E SimjeeM Stretton
Jan 1, 1989·Scandinavian Journal of Infectious Diseases·L JokipiiA M Jokipii

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