Kinetics of the glomerular ultrafiltration in the rat kidney. An experimental study.

Acta Physiologica Scandinavica
O KällskogM Wolgast

Abstract

The quantitative relation between the driving forces over the glomerular membrane and the glomerular plasma flow, on the one hand, and the single glomerular filtration rate (SNGFR), on the other, is still uncertain. Micropuncture measurements on Sprague-Dawley rats made it possible to calculate the net driving force over the glomerular membrane. The single glomerular plasma flow was determined from SNGFR and the single nephron filtration fraction (SNFF). The effective plasma flow was measured with PAH for total kidney and for superficial nephrons. The mean glomerular capillary pressure was found to be 62.6 mm Hg. The results indicate a net driving force of about 13 mm Hg at the distal end of the glomerular capillary. SNGFR was found to be 14.1 nl/min-100 g. SNFF amounted to about 0.27. The filtration fractions determined with the PAH method were in the same range. The results indicate a filtration disequilibrium, in contrast to those of Brenner et al. from measurements on a mutant Wistar rat strain. The filtration fractions seemed to be the same in all glomerular populations. It is clear that the SNGFR is pressure dependent. Our earlier findings of a nonautoregulation of the blood flow through the outer glomeruli were also conf...Continue Reading

References

Oct 1, 1975·Acta Physiologica Scandinavica·O KällskogM Wolgast
Nov 1, 1972·The American Journal of Physiology·C R RobertsonB M Brenner
Jul 1, 1972·Kidney International·R C BlantzJ M Green
Feb 1, 1972·The American Journal of Physiology·B M BrennerT M Daugharty
Oct 1, 1972·The American Journal of Physiology·M E AllisonC W Gottschalk
Aug 1, 1971·The Journal of Clinical Investigation·B M BrennerT M Daugharty
Jan 1, 1966·Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere·K H GertzH D Pagel
Apr 1, 1970·Microvascular Research·M IntagliettaW R Tompkins
Jan 1, 1969·Pflügers Archiv : European journal of physiology·K H GertzJ W Boylan
Jul 1, 1964·The American Journal of Physiology·C A WIEDERHIELMR F RUSHMER

❮ Previous
Next ❯

Citations

Nov 1, 1990·Pflügers Archiv : European journal of physiology·J M Davis
Oct 1, 1991·Pflügers Archiv : European journal of physiology·K M Denton, W P Anderson
Jan 1, 1981·Pflügers Archiv : European journal of physiology·K HermanssonM Wolgast
Apr 1, 1983·Pflügers Archiv : European journal of physiology·H M BrinkJ F Slegers
Apr 1, 1983·Pflügers Archiv : European journal of physiology·H M BrinkJ F Slegers
Oct 1, 1979·Pflügers Archiv : European journal of physiology·J Heller, V Horácek
Mar 1, 1980·Pflügers Archiv : European journal of physiology·K Felgenhauer
Jun 22, 1976·Pflügers Archiv : European journal of physiology·O KällskogM Wolgast
Jun 1, 1980·Pflügers Archiv : European journal of physiology·J Heller, V Horácek
Aug 1, 1981·Pflügers Archiv : European journal of physiology·B E Persson, A E Persson
Aug 1, 1981·Pflügers Archiv : European journal of physiology·B E Persson
Jul 21, 1977·The New England Journal of Medicine·B M Brenner, H D Humes
Mar 20, 2004·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Klaus H NeumannHans-Joachim Schurek
Oct 1, 1975·Acta Physiologica Scandinavica·O KällskogM Wolgast
Dec 1, 1977·Acta Physiologica Scandinavica·K AuklandG Naess
May 1, 1979·Acta Physiologica Scandinavica·K H Tønder, K Aukland
Jan 1, 1983·Acta Physiologica Scandinavica·O Källskog, M Wolgast
Sep 1, 1988·Acta Physiologica Scandinavica·A BayatiM Wolgast
Jun 4, 2010·Acta Physiologica·P PerssonF Palm
Mar 15, 2011·Acta Physiologica·M Wolgast, A E G Persson
Nov 1, 1979·The Journal of Clinical Investigation·L RaijA Michael
Aug 1, 1977·Kidney International·L G NavarR H Williams
Aug 1, 1981·Kidney International·M SteinhausenF D Dallenbach
Jan 1, 1985·Kidney International·B OdlindB Lindström
Aug 1, 1982·Kidney International·D E Oken
Jul 1, 1978·Kidney International·B J NorlénM Wolgast
Jan 1, 1983·Clinical and Experimental Dialysis and Apheresis·W F Finn
Jan 1, 1982·Scandinavian Journal of Urology and Nephrology·L KarlbergM Wolgast
Jul 15, 2015·Physiological Reports·Anita J TurnerA Erik G Persson
Aug 1, 1981·Acta Physiologica Scandinavica·P K JensenK Steven
Jan 1, 1981·CRC Critical Reviews in Biochemistry·C Helene, J C Maurizot
Mar 31, 2012·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Liselotte PihlFredrik Palm
Nov 1, 1979·Pflügers Archiv : European journal of physiology·P K Jensen, K Steven
Feb 1, 1981·Kidney International·D E OkenD C Mikulecky

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.