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Kinetochore phosphatases suppress autonomous kinase activity to control the spindle assembly checkpoint

bioRxiv

Nov 26, 2019

Marilia Henriques CordeiroAdrian T Saurin

Abstract

Local phosphatase regulation is critical for determining when phosphorylation signals are activated or deactivated. A typical example is the spindle assembly checkpoint (SAC) during mitosis, which regulates kinetochore PP1 and PP2A-B56 activities to switch-off signalling events at the c...read more

Mentioned in this Paper

KNTC1 protein, human
Protein Domain
Polo-like kinase 1
Protein Phosphatase 2A
Mitosis
Phosphoric Monoester Hydrolases
Phosphorylation
Phosphotransferases
BUB-3 protein, C elegans
Spindle Assembly Checkpoint
20
Paper Details
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Kinetochore phosphatases suppress autonomous kinase activity to control the spindle assembly checkpoint

bioRxiv

Nov 26, 2019

Marilia Henriques CordeiroAdrian T Saurin

DOI: 10.1101/856773

Abstract

Local phosphatase regulation is critical for determining when phosphorylation signals are activated or deactivated. A typical example is the spindle assembly checkpoint (SAC) during mitosis, which regulates kinetochore PP1 and PP2A-B56 activities to switch-off signalling events at the c...read more

Mentioned in this Paper

KNTC1 protein, human
Protein Domain
Polo-like kinase 1
Protein Phosphatase 2A
Mitosis
Phosphoric Monoester Hydrolases
Phosphorylation
Phosphotransferases
BUB-3 protein, C elegans
Spindle Assembly Checkpoint
20
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations
  • quote and clock

    No citations available

    This paper may not have been cited yet.
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