Kinin formation in the plasma and cerebral blood flow in under conditions of cerebral ischemia/reperfusion in rats during modulation of kinin system activity

Bulletin of Experimental Biology and Medicine
M V OrobeiY G Shatillo

Abstract

Suppression of kininogenesis is an adaptive phenomenon in cerebral ischemia/reperfusion in rats aimed at elimination of the no-reflow phenomenon. Hyperkininogenesis and suppression of kinin destruction are pathogenetically significant, because they augment the manifestations of no-reflow phenomenon during reperfusion following ischemia.

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