PMID: 11339480May 8, 2001Paper

Klebsiella brain abscess in adults

Infection
P-C LiliangH J Chen

Abstract

We analyzed the clinical manifestations and therapeutic outcomes of Klebsiella brain abscesses. The clinical data of 15 patients with Klebsiella brain abscesses, retrospectively collected over a 14-year period, were studied. The 15 patients included 13 cases of Klebsiella pneumoniae infection and two cases of Klebsiella oxytoca. All but one case were community-acquired infections. Locations of all of these abscesses were supratentorial. 12 cases involved a single abscess, and three involved multiple abscesses. Gas formation was also found in two cases (13%). Common predisposing factors included metastatic spread, chronic otitis media and neurosurgical procedures. Among these 15 patients, 11 were treated surgically and four received antibiotics alone. In total, 11 patients survived and four died, with an overall mortality rate of 26.7%. The clinical presentations and therapeutic outcomes varied according to the different Klebsiella species. While debilitating diseases were common in K. pneumoniae infections, they were not common in K. oxytoca infection. And while metastatic septic abscess is a well-known, devastating complication of K. pneumoniae septicemia, usually seen as a brain abscess with a gas-forming appearance, all of t...Continue Reading

Citations

Jan 21, 2009·Journal of Neurology·P WipflerJ Kraus
Nov 26, 2002·Clinical Neurology and Neurosurgery·Cheng-Shyuan RauBen-Chung Cheng
Oct 3, 2006·Journal of Neurology, Neurosurgery, and Psychiatry·Tsung-Han LeeCheng-Hsien Lu
Jun 25, 2014·Journal of Neuroradiology. Journal De Neuroradiologie·Carmine Franco MuccioCosma Andreula
Dec 6, 2014·The Kaohsiung Journal of Medical Sciences·Tsung-Ming SuShih-Wei Hsu
Jan 13, 2009·Journal of Korean Neurosurgical Society·Keun Tae Cho, Bong Jin Park
May 25, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·S-Y HsiaoC-H Lu
Feb 5, 2021·Journal of Medical Case Reports·Clay WuBrett Lindgren

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