Knowledge and stigma of latent tuberculosis infection in Brazil: implications for tuberculosis prevention strategies

BMC Public Health
Peter F RebeiroTimothy R Sterling

Abstract

Tuberculosis (TB) elimination requires treatment of millions of persons with latent M. tuberculosis infection (LTBI). LTBI treatment acceptance depends on population-wide TB knowledge and low stigma, but limited data are available on the relationship between stigma and knowledge. We assessed knowledge of TB disease and LTBI throughout Brazil and examined their association with TB stigma and incidence. We performed a nationwide survey with multi-stage probability design through AmericasBarometer from April-May 2017; the sample was representative of Brazil at regional and national levels. Knowledge of and stigma toward TB were assessed by validated survey questions. Survey-weighted responses of 1532 individuals suggest that 57% of the population knew LTBI can occur, and 90% would seek treatment for it. Regarding active TB, 85% knew TB symptoms, 70% reported they should avoid contact with someone with active TB, and 24% had stigma toward persons with TB (i.e., thought persons with tuberculosis should feel ashamed, or deserved their illness). In regression models adjusting for clinical and demographic variables, knowledge of LTBI was associated with increased stigma toward persons with TB (adjusted odds ratio [OR] = 2.13, 95% confi...Continue Reading

References

Jan 11, 2000·Journal of Community Health Nursing·P Kelly
Aug 12, 2009·Proceedings of the National Academy of Sciences of the United States of America·Laith J Abu-RaddadM Elizabeth Halloran
Jul 16, 2010·Public Health Reports·Andrew Courtwright, Abigail Norris Turner
May 13, 2011·Lancet·Jairnilson PaimJames Macinko
Oct 22, 2013·American Journal of Epidemiology·Kimberly M SheaC Robert Horsburgh
Jan 17, 2014·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·S-H Chang, J K Cataldo
Mar 26, 2015·PloS One·Anne Lia CremersMartin Peter Grobusch
Apr 14, 2016·PloS One·M Katherine CharlesUNKNOWN International epidemiology Databases to Evaluate AIDS (IeDEA) Collaboration
Nov 5, 2016·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·G M CraigA Ioannaki
Apr 4, 2017·Journal of Clinical Nursing·Li-Yun LeeChiung-Hui Fu
Oct 14, 2017·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·K MacintyreE M H Mitchell
Feb 17, 2018·Epidemiologia E Serviços De Saúde : Revista Do Sistema Unico De Saúde Do Brasil·Draurio Barreira
Feb 8, 2020·BMC Public Health·Daniel G DatikoPedro Suarez

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