Korean hemorrhagic fever: propagation of the etiologic agent in a cell line of human origin

Science
G R FrenchP W Lee

Abstract

The etiologic agent of Korean hemorrhagic fever has been propagated in a human cultured cell line derived from a carcinoma of the lung. The cells, described as type II, alveolar epithelial, support replication of the agent and successive passages. Antigen of the Korean hemorrhagic fever agent is readily detected in infected cells by means of direct or indirect fluorescent antibody techniques. Previous attempts to propagate this agent in vitro had been unsuccessful.

References

Mar 1, 1978·The Journal of Infectious Diseases·H W LeeK M Johnson
Jan 15, 1976·International Journal of Cancer. Journal International Du Cancer·M LieberG Todaro
Nov 1, 1973·Journal of the National Cancer Institute·D J GiardW P Parks

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Citations

Oct 23, 1997·Journal of Medical Virology·M D BowenN Nowotny
Jul 25, 1981·Lancet
May 5, 1984·Lancet·B Niklasson, J Le Duc
Nov 16, 2001·Microbes and Infection·D H KrügerA Lundkvist A
Dec 3, 1999·Microbes and Infection·C A Hart, M Bennett
Jul 1, 1983·Proceedings of the National Academy of Sciences of the United States of America·M C FrankoD C Gajdusek
Apr 1, 1997·Emerging Infectious Diseases·C Schmaljohn, B Hjelle
Jan 1, 1988·Scandinavian Journal of Infectious Diseases·A I SommerJ Dalrymple
Jan 1, 1982·Scandinavian Journal of Infectious Diseases·P W LeeK Nyström
Jan 1, 1995·Critical Reviews in Clinical Laboratory Sciences·B HjelleA A Scott
Oct 20, 2009·Vaccine·Connie Schmaljohn
Dec 17, 2004·Journal of Medical Virology·Svetlana F KhaiboullinaStephen C St Jeor
Oct 8, 2008·Immunological Reviews·Günther SchönrichRainer G Ulrich
Mar 1, 1989·Journal of Medical Virology·L ZöllerG Darai
Oct 1, 1985·Journal of Medical Virology·K T McKeeC J Peters
Jan 1, 1983·Scandinavian Journal of Infectious Diseases·B NiklassonJ Dalrymple
Nov 2, 1999·Virology·J I KangB Y Ahn
Apr 19, 2013·Clinical and Experimental Vaccine Research·Myoung-Don Oh, Jong-Koo Lee
Jul 9, 1999·Reviews in Medical Virology·M KanervaA Vaheri
Aug 1, 1983·Revista de saúde pública·L B Iversson
Oct 1, 1994·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·K H Yoo, Y Choi
Aug 1, 1994·Annals of Tropical Medicine and Parasitology·C A Hart, M Bennett
Nov 2, 2019·Infection & chemotherapy·Ji Yun NohJin Won Song
Aug 1, 1997·FEMS Immunology and Medical Microbiology·C J Peters

❮ Previous
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