Kounis syndrome associated with hypersensitivity to hymenoptera stings

International Journal of Cardiology
John S KogiasSotirios K Anifadis

Abstract

Hymenoptera stings can induce acute coronary syndromes by different pathogenetic mechanisms including direct action of the venom constituents on the coronary endothelium or allergic reaction with mediators acting on the coronary vasculature. Two patients were stung by wasps and honeybees and developed Kounis syndrome as a consequence of allergic reaction. Kounis syndrome is the concurrence of acute coronary syndromes with mast cell activation induced by allergic or hypersensitivity and anaphylactic of anaphylactoid reactions. It is caused via inflammatory mediators released through mast cell activation. The patients had pre-existing coronary artery disease (type II variant of Kounis syndrome) and the allergic reaction induced by hymenoptera stings seems to have triggered inflammatory mediator release. The pathophysiology and clinical implications of this association are discussed.

References

Aug 16, 2003·Clinical Cardiology·Krzysztof J FilipiakAndrzej Czlonkowski
Nov 25, 2003·Southern Medical Journal·John E Moffitt
Aug 19, 2004·The Journal of Allergy and Clinical Immunology·Simon G A Brown
Nov 5, 2004·The New England Journal of Medicine·Theodore M Freeman
Jun 2, 2005·Journal of the Royal Society of Medicine·Nicholas G KounisConstantinos M Koutsojannis
Jun 9, 2005·Annals of Emergency Medicine·Susan M RohrKevin H Silver
Jul 8, 2005·Acta Cardiologica·Andreas MazarakisDimitrios Alexopoulos
Jul 19, 2005·Heart and Vessels·George D SoufrasConstantinos M Koutsojannis

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Citations

Nov 5, 2011·Future Cardiology·Nicholas G KounisJohn Goudevenos
May 13, 2009·Vojnosanitetski pregled. Military-medical and pharmaceutical review·Danica Cvetković-MatićVesna Stojanov
Sep 2, 2014·International Journal of Cardiology·Alejandro Gutiérrez BarriosJavier Benezet Mazuecos
Dec 14, 2011·Medicina intensiva·P Rico CepedaM M Rodríguez Aguirregabiria
Jun 29, 2010·The American Journal of Emergency Medicine·Joon Min ParkMin Joung Kim
May 12, 2009·International Journal of Cardiology·Erkan IlhanOzer Soylu
Mar 31, 2009·The Journal of Emergency Medicine·Sofiene RekikJean Lou Hirsch
Feb 11, 2009·International Journal of Cardiology·George AlmpanisNicholas G Kounis
Jul 25, 2008·International Journal of Cardiology·Jaspal S TaggarTeri Millane
Jun 17, 2008·International Journal of Cardiology·Dimitrios Z MytasVlassios N Pyrgakis
Apr 2, 2008·International Journal of Cardiology·Salvatore PatanèSebastiano Coglitore
Jun 26, 2007·International Journal of Cardiology·George N KounisNicholas G Kounis
Apr 20, 2007·International Journal of Cardiology·O QuerciaG F Stefanini
Jan 16, 2009·International Journal of Cardiology·Salvatore PatanèClaudia Cimino
Nov 26, 2013·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Ramon LleonartMercè Corominas
Apr 8, 2016·Annals of Cardiac Anaesthesia·Hamed AminiahidashtiAli Morad Heidari Gorji
Sep 23, 2008·International Journal of Cardiology·John S KogiasNicholas G Kounis
May 22, 2010·International Journal of Cardiology·Weeranun DechyapiromKenneth Nugent
Jul 8, 2010·International Journal of Cardiology·Sani Namik MuratRamazan Akdemir
Apr 30, 2013·International Journal of Cardiology·Erkan IlhanMetin Gürsürer
Feb 19, 2013·International Journal of Cardiology·Marita Nittner-MarszalskaBernard Panaszek
Jun 6, 2016·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Miguel Ángel Blasco-NavalpotroFrancisco Javier Seoane-Leston
Sep 11, 2010·Expert Review of Clinical Immunology·Murat Biteker
Oct 12, 2010·Southern Medical Journal·Pablo R Lopez, Alan N Peiris
Aug 6, 2020·Journal of Family Medicine and Primary Care·Ashok SunderAbha Singh

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