PMID: 25735388Mar 5, 2015Paper

KRT13, FAIM2 and CYP2W1 mRNA expression in oral squamous cell carcinoma patients with risk habits

Asian Pacific Journal of Cancer Prevention : APJCP
Firstine Kelsi HartantoRosnah Binti Zain

Abstract

Expression of KRT13, FAIM2 and CYP2W1 appears to be influenced by risk habits, thus exploring the associations of these genes in oral squamous cell cancer (OSCC) with risk habits, clinico-pathological parameters and patient survival may be beneficial in identifying relevant biomarkers with different oncogenic pathways. cDNAs from 41 OSCC samples with and without risk habits were included in this study. Quantitative real-time PCR was used to analyze KRT13, FAIM2 and CYP2W1 in OSCC. The housekeeping gene (GAPDH) was used as an endogenous control. Of the 41 OSCC samples, KRT13 was down-regulated in 40 samples (97.6%), while FAIM2 and CYP2W1 were down-regulated in 61.0% and 48.8%, respectively. Overall, there were no associations between KRT13, FAIM2 and CYP2W1 expression with risk habits, selected socio-demographic and clinico-pathological parameters and patient survival. Although this study was unable to show significance, there were some tendencies in the associations of KRT13, FAIM2 and CYP2W1 expression in OSCC with selected clinic-pathological parameters and survival.

References

Oct 27, 1999·Proceedings of the National Academy of Sciences of the United States of America·N V SomiaI M Verma
Jul 1, 2005·Toxicology and Applied Pharmacology·Maria KarlgrenMagnus Ingelman-Sundberg
Jan 24, 2006·Biochemical and Biophysical Research Communications·Maria KarlgrenMagnus Ingelman-Sundberg
Nov 6, 2007·Pharmacogenomics·Alvin GomezMagnus Ingelman-Sundberg
Aug 5, 2008·Oral Oncology·Stefano Petti
Sep 23, 2008·Oral Oncology·Saman Warnakulasuriya
Jan 3, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·David EdlerPeter Ragnhammar
Jun 23, 2010·Molecular Pharmacology·Clinton R NishidaPaul R Ortiz de Montellano
Jan 7, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Arno ReichJörg B Schulz
Feb 26, 2011·International Journal of Cancer. Journal International Du Cancer·Jacques FerlayDonald Maxwell Parkin
Dec 19, 2012·Asian Pacific Journal of Cancer Prevention : APJCP·Kulchaya LoyhaDonald Maxwell Parkin
Dec 3, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Sree Vidya Krishna RaoRichard Logan
Aug 16, 2014·Asian Pacific Journal of Cancer Prevention : APJCP·Bhawna Gupta, Newell W Johnson

❮ Previous
Next ❯

Citations

Jun 4, 2016·Drug Metabolism Reviews·Jia GuoMagnus Ingelman-Sundberg
Oct 4, 2016·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·Yan Pan, Eng Chin Ong
Aug 1, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Sanniya FarrukhShahid Pervez

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Shanghai kou qiang yi xue = Shanghai journal of stomatology
Xiao-zhi LvChenping Zhang
ORL; Journal for Oto-rhino-laryngology and Its Related Specialties
Danielle Resende CamisascaSimone de Queiroz Chaves Lourenço
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
Yang ShaoDong Leng
© 2022 Meta ULC. All rights reserved