Krüppel acts as a gap gene regulating expression of hunchback and even-skipped in the intermediate germ cricket Gryllus bimaculatus

Developmental Biology
Taro MitoSumihare Noji

Abstract

In Drosophila, a long germ insect, segmentation occurs simultaneously across the entire body. In contrast, in short and intermediate germ insects, the anterior segments are specified during the blastoderm stage, while the remaining posterior segments are specified during later stages. In Drosophila embryos, the transcriptional factors coded by gap genes, such as Krüppel, diffuse in the syncytial environment and regulate the expression of other gap, pair-rule, and Hox genes. To understand the segmentation mechanisms in short and intermediate germ insects, we investigated the role of Kr ortholog (Gb'Kr) in the development of the intermediate germ insect Gryllus bimaculatus. We found that Gb'Kr is expressed in a gap pattern in the prospective thoracic region after cellularization of the embryo. To determine the function of Gb'Kr in segmentation, we analyzed knockdown phenotypes using RNA interference (RNAi). Gb'Kr RNAi depletion resulted in a gap phenotype in which the posterior of the first thoracic through seventh abdominal segments were deleted. Analysis of the expression patterns of Hox genes in Gb'Kr RNAi embryos indicated that regulatory relationships between Hox genes and Kr in Gryllus differ from those in Oncopeltus, anoth...Continue Reading

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Citations

Jul 24, 2008·PloS One·Koichi FujimotoKunihiko Kaneko
Oct 12, 2010·Cellular and Molecular Life Sciences : CMLS·Johannes Jaeger
Dec 8, 2009·Annual Review of Entomology·Xavier Bellés
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Mar 27, 2016·Developmental Biology·Hajime Nakao
May 4, 2010·Developmental Biology·Mónica García-SolacheMichael Akam
Jun 11, 2011·Developmental Biology·Ralf JanssenWim G M Damen
Oct 12, 2016·Arthropod Structure & Development·Ralf Janssen
Apr 25, 2015·Developmental Biology·Seth Donoughe, Cassandra G Extavour
May 25, 2016·Pest Management Science·Elane FishilevichBlair D Siegfried
Jul 21, 2009·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Aska HamadaSumihare Noji
Apr 19, 2007·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Wim G M Damen
Nov 30, 2019·Mechanisms of Development·Jinsung Lim, Chong Pyo Choe
Dec 23, 2009·Developmental Biology·Megan J WilsonPeter K Dearden
May 14, 2010·Current Opinion in Genetics & Development·Taro MitoSumihare Noji

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