Kuopio birth cohort - design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child

BMC Pregnancy and Childbirth
Pasi HuuskonenMarkku Pasanen

Abstract

A Finnish joint research effort Kuopio Birth Cohort (KuBiCo) seeks to evaluate the effects of genetics, epigenetics and different risk factors (medication, nutrition, lifestyle factors and environmental aspects) during pregnancy on the somatic and psychological health status of the mother and the child. KuBiCo will ultimately include information on 10,000 mother-child pairs who have given their informed consent to participate in this cohort. Identification of foetal health risk factors that can potentially later manifest as disease requires a repository of relevant biological samples and a flexible open up-to-date data handling system to register, store and analyse biological, clinical and questionnaire-based data. KuBiCo includes coded questionnaire-based maternal background data gathered before, during and after the pregnancy and bio-banking of maternal and foetal samples that will be stored in deep freezers. Data from the questionnaires and biological samples will be collected into one electronic database. KuBiCo consists of several work packages which are complementary to each other: Maternal, foetal and placental metabolism and omics; Paediatrics; Mental wellbeing; Prenatal period and delivery; Analgesics and anaesthetics ...Continue Reading

References

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May 18, 2016·Reproductive Toxicology·Pasi HuuskonenMarkku Pasanen
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Citations

Jan 18, 2020·Acta Anaesthesiologica Scandinavica·Mari KinnunenMerja Kokki
Apr 5, 2020·European Journal of Nutrition·Anni LehtonenMarko Lehtonen

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Software Mentioned

KuBiCo
Ingenuity Pathway Analysis ( IPA
Revolution R Enterprise
WebKuBiCo

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