L-Amino acid oxidases from microbial sources: types, properties, functions, and applications

Applied Microbiology and Biotechnology
Gazi Sakir HossainJian Chen

Abstract

L-Amino acid oxidases (LAAOs), which catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia, are flavin adenine dinucleotide-containing homodimeric proteins. L-Amino acid oxidases are widely distributed in diverse organisms and have a range of properties. Because expressing LAAOs as recombinant proteins in heterologous hosts is difficult, their biotechnological applications have not been thoroughly advanced. LAAOs are thought to contribute to amino acid catabolism, enhance iron acquisition, display antimicrobial activity, and catalyze keto acid production, among other roles. Here, we review the types, properties, structures, biological functions, heterologous expression, and applications of LAAOs obtained from microbial sources. We expect this review to increase interest in LAAO studies.

References

Dec 8, 1976·Molecular & General Genetics : MGG·F C Franklin, W A Venables
Feb 1, 1975·Journal of Bacteriology·J A Duerre, S Chakrabarty
Apr 15, 1991·FEMS Microbiology Letters·D M Niedermann, K Lerch
Jun 15, 1989·European Journal of Biochemistry·A BöhmerH G Müller
Jan 1, 1972·Biochimie·J PelmontA M Rossat
Jun 1, 1971·Analytical Chemistry·M Roth
Jan 1, 1982·Molecular & General Genetics : MGG·L Sikora, G A Marzluf
Nov 1, 1984·Journal of Bacteriology·R M DeBusk, S Ogilvie
Feb 14, 1980·Biochimica Et Biophysica Acta·E K Pistorius, H Voss
Jan 1, 1981·Journal of Bacteriology·E K Yu, I W DeVoe
Aug 1, 1982·European Journal of Biochemistry·E K Pistorius, H Voss
Aug 1, 1996·Applied and Environmental Microbiology·S G JamesS Kjelleberg
Jan 1, 1997·Cancer Chemotherapy and Pharmacology·K MoynihanH S Friedman
Mar 25, 1998·Analytical Chemistry·T HuangF W Scheller
Feb 9, 2000·Bioscience, Biotechnology, and Biochemistry·E TakahashiT Yoshimoto
Nov 4, 2000·Archives of Pharmacal Research·M Y AhnY S Kim
Oct 16, 2001·Toxicon : Official Journal of the International Society on Toxinology·Y SakuraiY Fujimura
Aug 15, 2002·Toxicon : Official Journal of the International Society on Toxinology·Xiao-Yan Du, Kenneth J Clemetson
Nov 19, 2002·FEBS Letters·Tatsuya EharaTakahide Tsuchiya
Apr 18, 2003·Protein Expression and Purification·Birgit Geueke, Werner Hummel
Feb 1, 1956·The Biochemical Journal·H BLASCHKO, D B HOPE
Mar 3, 2006·Acta Crystallographica. Section F, Structural Biology and Crystallization Communications·Annette FaustDietmar Schomburg
Jun 5, 2007·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Achim E GauElfriede K Pistorius

❮ Previous
Next ❯

Citations

Apr 16, 2015·Applied Microbiology and Biotechnology·Tzi Bun NgAlaa El-Din Bekhit
Feb 19, 2015·Protein Engineering, Design & Selection : PEDS·Joseph B Lim, Hadley D Sikes
Jul 17, 2016·Journal of Structural Biology·Yingchen JuHuihao Zhou
Nov 9, 2016·Toxicon : Official Journal of the International Society on Toxinology·Yang YuePengcheng Li
Dec 18, 2016·Applied Microbiology and Biotechnology·Katharina HahnGabriele Fischer von Mollard
Dec 21, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Katharina HahnGabriele Fischer von Mollard
Sep 30, 2017·Phytotherapy Research : PTR·Anja KlančnikJerica Sabotič
Jun 13, 2020·Biotechnology and Bioengineering·Xiulai ChenLiming Liu
Dec 14, 2018·Marine Drugs·Andrés Andreo-VidalJonatan C Campillo-Brocal
Jul 8, 2017·3 Biotech·Gašper ŽunJerica Sabotič
Jun 23, 2018·Bioprocess and Biosystems Engineering·Zhaojuan ZhengJia Ouyang
Jan 19, 2017·Angewandte Chemie·Chengzhang FuRolf Müller
Jun 9, 2018·Applied Biochemistry and Biotechnology·Longbao ZhuZhemin Zhou
Jan 12, 2019·Applied Microbiology and Biotechnology·Svenja BloessGabriele Fischer von Mollard
Mar 4, 2021·Developmental and Comparative Immunology·Jiann-Horng LeuHao-Ching Wang
Nov 19, 2018·Current Opinion in Chemical Biology·Yasuhisa Asano, Kazuyuki Yasukawa
Aug 7, 2021·The Journal of Biological Chemistry·Sayaka SugiuraSohei Ito

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bioinformatics in Biomedicine

Bioinformatics in biomedicine incorporates computer science, biology, chemistry, medicine, mathematics and statistics. Discover the latest research on bioinformatics in biomedicine here.

Related Papers

Applied Microbiology and Biotechnology
Davide BifulcoGianluca Molla
Applied Microbiology and Biotechnology
Loredano PollegioniGianluca Molla
Applied Biochemistry and Biotechnology
Zhiliang Yu, Hua Qiao
© 2021 Meta ULC. All rights reserved