L-carnitine Improved the Cardiac Function via the Effect on Myocardial Fatty Acid Metabolism in a Hemodialysis Patient

Internal Medicine
Mai KanekoRyuichi Furuya

Abstract

Patients on hemodialysis often have carnitine deficiency. We herein report a woman who experienced the dramatic improvement of cardiac dysfunction after intravenous L-carnitine administration. We also investigated the myocardial fatty acid metabolism using 123I-labeled β-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) single-photon emission computed tomography (SPECT) before and after L-carnitine therapy, and the impaired metabolism was ameliorated. Taken together, these findings indicate that L-carnitine therapy improved cardiac dysfunction via the amelioration of the abnormal myocardial fatty acid metabolism, at least in part.

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Citations

Aug 28, 2018·Internal Medicine·Takashi Maruyama, Masanori Abe
Jan 4, 2021·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Kristen SgambatAsha Moudgil
Mar 13, 2021·Clinical Medicine Insights. Cardiology·Kartheek GarikapatiKrishna Echampati

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