PMID: 6108539Dec 1, 1980Paper

L-glutamate as possible neurotransmitter in the ampullae of Lorenzini of the skate

Neuroscience Letters
G N AkoevN O Volpe

Abstract

Effects of Mg2+, L-glutamate (L-Glu) and L-glutamic acid diethylester (GDEE) on resting and evoked activities of the ampullae of Lorenzini were studied in marine skates (Raja clavata). Perfusion of the basal membrane with 10(-4)-10(-5) M L-Glu produced significant and reversible changes in resting firing rate depending on initial resting rate. When synaptic transmission was blocked by perfusion with elevated Mg2+, the resting activity was restored if L-Glu (10(-4)-10(-5) M) was added. GDEE (10(-3)-10(-4) M) blocked the synaptic transmission. The results are consistent with the view that L-Glu is the synaptic transmitter in the ampullae of Lorenzini of the skate.

References

Nov 1, 1972·The Journal of General Physiology·S Obara, M V Bennett
Jan 11, 1974·Pflügers Archiv : European journal of physiology·H Hensel

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Citations

Aug 11, 1981·Molecular and Cellular Biochemistry·M Baudry, G Lynch
Jun 3, 1983·European Journal of Pharmacology·M BaudryG Lynch
Jan 1, 1987·Comparative Biochemistry and Physiology. A, Comparative Physiology·G N AkoevT Szabo
Mar 1, 1995·Comparative Biochemistry and Physiology. Part A, Physiology·G N Akoev
Jan 1, 1987·Progress in Neurobiology·M L Mayer, G L Westbrook
Feb 1, 1995·Progress in Neurobiology·C HildebrandC S Johansson
Nov 1, 1992·Hearing Research·G ZuccaP Valli
Jan 1, 1983·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G N AkoevN O Sherman
Jan 1, 1986·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·G L JenisonR P Bobbin
Mar 1, 1984·The Annals of Otology, Rhinology, and Laryngology·C DechesneA Sans
Sep 1, 1984·Journal of Neurobiology·A Van Harreveld

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