Label-free detection of antigen protein using a metal mesh device surface-modified by an antibody

Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry
Hirokazu SetoYoshiko Miura

Abstract

A biosensor for protein detection was developed using antibody-immobilized metal mesh devices. Antihemoglobin antibodies were covalently immobilized on a metal mesh device. Extraordinary transmission with a dipped structure was observed for a metal mesh device immobilized with antihemoglobin antibodies as well as for the original metal mesh device. Hemoglobin in the mixture solution containing albumin at a hundred-fold concentration was detectable using antihemoglobin-immobilized MMDs. The detectability using the antihemoglobin-immobilized metal mesh device was similar to that of a commercially-available kit for the qualitative determination of hemoglobin.

References

Apr 22, 2006·Optics Letters·F MiyamaruE Kato
Aug 5, 2008·Biosensors & Bioelectronics·Peter Durand SkottrupAnnemarie Fejer Justesen
Mar 6, 2012·Biosensors & Bioelectronics·Timothy R J HolfordSéamus P J Higson
Jul 3, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Hirokazu SetoYoshiko Miura
Jun 7, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yuhei TeradaYoshiko Miura

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Citations

Jul 13, 2018·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Seiji KambaYoshiko Miura
Feb 5, 2019·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Hirokazu SetoHiroyuki Shinto
Oct 11, 2017·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Taiga AjiriManabu Tokeshi
Sep 12, 2017·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Seiji KambaYoshiko Miura
May 11, 2018·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Seiji KambaYoshiko Miura

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