Label-free electrical detection using carbon nanotube-based biosensors.

Sensors
Kenzo Maehashi, Kazuhiko Matsumoto

Abstract

Label-free detections of biomolecules have attracted great attention in a lot of life science fields such as genomics, clinical diagnosis and practical pharmacy. In this article, we reviewed amperometric and potentiometric biosensors based on carbon nanotubes (CNTs). In amperometric detections, CNT-modified electrodes were used as working electrodes to significantly enhance electroactive surface area. In contrast, the potentiometric biosensors were based on aptamer-modified CNT field-effect transistors (CNTFETs). Since aptamers are artificial oligonucleotides and thus are smaller than the Debye length, proteins can be detected with high sensitivity. In this review, we discussed on the technology, characteristics and developments for commercialization in label-free CNT-based biosensors.

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Citations

Apr 21, 2012·Lab on a Chip·Mariana Medina-SánchezArben Merkoçi
Mar 25, 2014·ACS Nano·Max Marcel ShulakerSubhasish Mitra
Aug 3, 2013·Advanced Drug Delivery Reviews·Sebastian KrussMichael S Strano
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Jan 15, 2021·Diagnostics·Ragaa Abd-Ellatief, Maha Ragaa Abd-Ellatief
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Feb 6, 2019·Nano Letters·Steven G NoyceAaron D Franklin

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Methods Mentioned

BETA
biosensors
biosensor
chip
chips
thermal
chemical vapor deposition

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