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Label-free multiphoton imaging of β -amyloid plaques in Alzheimer's disease mouse models

Neurophotonics

Oct 1, 2019

Shu WangJian-xin Chen

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Abstract

β -Amyloid ( A β ) plaque, representing the progressive accumulation of the protein that mainly consists of A β , is one of the prominent pathological hallmarks of Alzheimer's disease (AD). Label-free imaging of A β plaques holds the potential to be a histological examinat...read more

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Alzheimer's Disease
Biological Markers
Diagnostic Imaging
Laboratory mice
Intracellular
Disease Progression
Extracellular
Microscopy, Fluorescence, Multiphoton
Beta protein
Mouse Model
1
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Label-free multiphoton imaging of β -amyloid plaques in Alzheimer's disease mouse models

Neurophotonics

Oct 1, 2019

Shu WangJian-xin Chen

PMID: 31737743

DOI: 10.1117/1.nph.6.4.045008

Abstract

β -Amyloid ( A β ) plaque, representing the progressive accumulation of the protein that mainly consists of A β , is one of the prominent pathological hallmarks of Alzheimer's disease (AD). Label-free imaging of A β plaques holds the potential to be a histological examinat...read more

Mentioned in this Paper

Alzheimer's Disease
Biological Markers
Diagnostic Imaging
Laboratory mice
Intracellular
1

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