Label-Free Simultaneous Analysis of Fe(III) and Ascorbic Acid Using Fluorescence Switching of Ultrathin Graphitic Carbon Nitride Nanosheets

ACS Applied Materials & Interfaces
Xinrong GuoLishi Wang

Abstract

A simple chemical oxidation and ultrasound exfoliation method has been developed to synthesize the two-dimensional and ultrathin-layer materials-graphitic carbon nitride nanosheets (g-C3N4 NNs). The prepared ultrathin g-C3N4 NNs display strong fluorescence and stability, including good photostability and excellent antisalt ability. Herein, a new "on-off-on" fluorescent switching sensor is designed. The iron ion (Fe3+) has an ultrasensitive response to quench the fluorescence of g-C3N4 NNs based on the synergistic effect between inner filter effect and photoinduced electron transfer. The linear limit for Fe3+ was from 0.05 to 30 μmol L-1 with a detection limit of 0.018 μmol L-1. Meanwhile, the fluorescence of g-C3N4 NNs can recover through the redox reaction between Fe3+ and ascorbic acid (AA). In addition, the linear range for AA was from 0.2 to 112.5 μmol L-1 with a 0.086 μmol L-1 detection limit. The proposed method exhibited rapid response, excellent selectivity, wide detection range, and low detection limit for simultaneous analysis of Fe3+ and AA, and it was applied for the determination of Fe3+ and AA in water sample and human serum with satisfactory results.

References

Nov 11, 2008·Nature Materials·Xinchen WangMarkus Antonietti
Nov 8, 2012·Chemical Communications : Chem Comm·Jianghua LiYilin Chen
Sep 1, 2015·ACS Applied Materials & Interfaces·Ruihua GuoNicolas H Voelcker
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Feb 7, 2018·ACS Applied Materials & Interfaces·Dong PengJian-Ding Qiu

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Citations

May 19, 2020·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Wei ZengYinhui Yi
Nov 19, 2020·Chemical Society Reviews·Nasuha RohaizadMartin Pumera
Jan 29, 2021·Journal of Analytical Methods in Chemistry·Hui XiaYuesuo Yang
Jun 22, 2021·Frontiers in Immunology·Gabriela H Da SilvaDiego Stéfani T Martinez
Nov 16, 2021·Luminescence : the Journal of Biological and Chemical Luminescence·Yalei LiuYufang Hu

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