PMID: 1214018Oct 1, 1975Paper

Lability of human creatine kinase isoenzymes at 37 degrees C: a complication of electrophoretic separation

Journal of Clinical Pathology
D A Nealon, A R Henderson

Abstract

The activity of the brain specific isoenzyme of creatine kinase is shown to fall off rapidly at 37 degrees C, particularly in the presence of albumin. Dithiothreitol cannot reverse this lability. The implications of this finding suggest that electrophoretic techniques which use incubation methods to detect the brain specific isoenzyme of creatine kinase may underestimate the true activity.

References

Jul 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·A F Smith
Aug 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·H Somer, A Konttinen
Feb 9, 1974·Lancet·G M Hall, D Lister
May 6, 1974·The American Journal of Cardiology·R RobertsB E Sobel
Aug 1, 1974·Archives of Neurology·I Goto
Sep 1, 1969·Proceedings of the National Academy of Sciences of the United States of America·A L SherwinJ A Bulcke
Feb 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·H Somer, A Konttinen
Mar 1, 1972·Anesthesia and Analgesia·E K ZsigmondK Flynn
Jul 1, 1968·Clinica Chimica Acta; International Journal of Clinical Chemistry·T D Trainer, D Gruenig

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Citations

Dec 1, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·H W ChoD Goode
Mar 15, 1977·Clinica Chimica Acta; International Journal of Clinical Chemistry·A O VladutiuJ H Siegel
Jan 31, 1980·Clinica Chimica Acta; International Journal of Clinical Chemistry·R D FeldD L Witte
Oct 23, 1980·Clinica Chimica Acta; International Journal of Clinical Chemistry·M H Lerner, A J Friedhoff
Sep 1, 1981·Clinica Chimica Acta; International Journal of Clinical Chemistry·J P ChapelleC Heusghem
Sep 16, 1985·Clinica Chimica Acta; International Journal of Clinical Chemistry·F Kanemitsu, T Okigaki
Jul 1, 1977·Journal of Clinical Pathology·D A Nealon, A R Henderson
Jul 1, 1977·Journal of Clinical Pathology·K C Ashley
Aug 1, 1982·Acta Anaesthesiologica Scandinavica·A RudehillN G Wahlgren
Oct 1, 1981·Journal of Neurosurgery·M KasteA Konttinen
Jan 1, 1981·The British Journal of Psychiatry : the Journal of Mental Science·C G FairburnD Burt

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