Laboratory and clinical characteristics of human West Nile virus infections during 2011 outbreak in southern Greece

Vector Borne and Zoonotic Diseases
G VrioniA Tsakris

Abstract

During the summer-autumn of 2011, a human outbreak of West Nile virus (WNV) infection occurred in southern Greece, following the first outbreak during 2010 in northern Greece. An investigation was performed to analyze laboratory diagnosis, geographic distribution, and clinical features of WNV cases in southern Greece. Serum and cerebrospinal fluid (CSF) specimens from all patients seeking laboratory diagnosis for suspected WNV infection were tested for the presence of specific WNV immunoglobulin M (IgM) and IgG antibodies. Detection of WNV RNA in CSF and whole blood samples was accomplished by real-time PCR. During August-October of 2011, 31 confirmed or probable cases of WNV infection were identified. In 25 of them, individuals experienced severe neurological manifestations and were classified as WNV neuroinvasive disease cases. Risk factors such as advanced age, hypertension, and diabetes mellitus were identified in most cases with neurological complications. As many as 25 of the WNV cases occurred in the broader region of Athens; the majority of them (17 cases) were identified in municipalities of Eastern Attica, located almost 40 km from the metropolitan area of Athens and 500 km from Central Macedonia, where the 2010 WNV o...Continue Reading

References

Jun 16, 2001·The New England Journal of Medicine·D NashUNKNOWN 1999 West Nile Outbreak Response Working Group
Aug 6, 2002·Annals of Internal Medicine·Lyle R Petersen, Anthony A Marfin
Sep 1, 1964·Transactions of the Royal Society of Tropical Medicine and Hygiene·M PAVLATOS, C E SMITH
Mar 17, 2004·Vector Borne and Zoonotic Diseases·Daniel R O'LearyGrant L Campbell
Sep 9, 2004·Annals of Internal Medicine·John T WatsonSusan I Gerber
Oct 13, 2004·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Deepali KumarAtul Humar
Apr 12, 2005·Transfusion·Steven KleinmanUNKNOWN NHLBI Retrovirus Epidemiology Study (REDS)
Jan 18, 2006·Annual Review of Medicine·Edward B Hayes, Duane J Gubler
Dec 21, 2006·Transfusion·Susan P MontgomeryUNKNOWN 2003 West Nile Virus Transfusion-Associated Transmission Investigation Team
Jan 24, 2007·Lancet Neurology·Laura D KramerPei-Yong Shi
Sep 21, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Duane J Gubler
Feb 9, 2008·Emerging Infectious Diseases·Cynthia M JeanCarol A Glaser
Aug 27, 2010·Vector Borne and Zoonotic Diseases·Anna PapaConcetta Castilletti
Sep 3, 2010·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·A PapaT Panagiotopoulos
Sep 30, 2010·The Journal of Infectious Diseases·Shimian ZouSusan L Stramer
Oct 2, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·F MaguranoL Nicoletti
Oct 5, 2012·Clinical Microbiology Reviews·Tonya M ColpittsErol Fikrig

❮ Previous
Next ❯

Citations

Apr 29, 2014·Pathogens and Global Health·Samira RiabiMahjoub Aouni
Jul 15, 2015·The Lancet Infectious Diseases·Hetal PatelMark P Nelder
Dec 12, 2018·The American Journal of Tropical Medicine and Hygiene·Maria MavrouliAthanassios Tsakris
Oct 30, 2018·Frontiers in Microbiology·Yaniv LustigElla Mendelson

❮ Previous
Next ❯

Methods Mentioned

BETA
enzyme-linked immunosorbent assays
ELISAs
ELISA
PCR
nucleic acid amplification

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
Kostas DanisJ Kremastinou
Emerging Infectious Diseases
Kostas DanisTakis Panagiotopoulos
Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
L BarzonG Palù
© 2021 Meta ULC. All rights reserved