Laboratory diagnosis of human T-lymphotropic virus in Brazil: assays, flowcharts, challenges, and perspectives.

Revista Da Sociedade Brasileira De Medicina Tropical
Adele Caterino-De-AraujoCarolina Rosadas

Abstract

We present a data analysis and review of recent studies regarding the laboratory diagnosis of human T-lymphotropic virus 1 and 2 (HTLV-1/2) infections in Brazil. Target populations, available diagnostic serological assays (screening and complementary tests), molecular assays (in-house), causes of false-positive and false-negative results, and flowcharts were analyzed. A table presents the target populations, two diagnostic flowcharts (depending on laboratory infrastructure and study population), and recent research that may improve how HTLV-1/2 is diagnosed in Brazil. Our results support the implementation of public policies to reduce HTLV-1/2 transmission and its associated diseases.

References

Feb 26, 2011·Journal of Virological Methods·Emanuela A S CostaAdele Caterino-de-Araujo
Jun 28, 2011·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Allison WatersWilliam W Hall
Aug 6, 2013·Journal of Virological Methods·Carolina RosadasMarzia Puccioni-Sohler
Mar 28, 2017·The Brazilian Journal of Infectious Diseases : an Official Publication of the Brazilian Society of Infectious Diseases·Karoline Rodrigues CamposAdele Caterino-de-Araujo
Sep 21, 2018·Journal of Clinical Microbiology·Vanessa da Silva BritoBernardo Galvão-Castro
May 28, 2019·Frontiers in Microbiology·Carolina Rosadas, Graham P Taylor
Sep 13, 2019·PLoS Neglected Tropical Diseases·Carolina RosadasGraham P Taylor
Oct 17, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Marzia Puccioni-SohlerThessika Hialla Almeida Araújo
Feb 12, 2020·The American Journal of Tropical Medicine and Hygiene·Sandra GallegoSilvia Nates
Oct 2, 2020·MSphere·Karoline Rodrigues Campos, Adele Caterino-de-Araujo
Mar 9, 2021·Revista Da Sociedade Brasileira De Medicina Tropical·Carolina RosadasGraham Philip Taylor

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