Laboratory diagnosis of intravascular catheter associated sepsis

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
P J Collignon, R Munro

Abstract

Many different methods have been employed to aid in the laboratory diagnosis of intravascular catheter associated infection. However, because of differences in patient populations, the definition of catheter sepsis and types of catheters, comparison of these studies is difficult. Of even more fundamental importance, the question of the pathogenesis of intravascular catheter associated sepsis (i.e. whether the microorganisms migrate to the intravascular space via the internal or external surface of the catheter) has not been resolved and is the subject of ongoing controversy. Semiquantitative culture of catheter tips would appear the easiest and most labour-efficient method available at present to diagnose catheter related infection. With central vein catheter tips, however, a cut-off level below 15 CFU per plate should be adopted as indicating a positive test result, particularly in patient populations with a high prevalence of catheter associated infection. Methods for non-quantitative broth culture of catheter tips are likely to be more sensitive than the semiquantitative method, but are less specific. Quantitative broth methods improve the specificity, but because of the labour costs involved appear not to offer much advanta...Continue Reading

References

Apr 1, 1979·Archives of Internal Medicine·E J WingA Winkelstein
Jun 9, 1977·The New England Journal of Medicine·D G MakiH W Sarafin
Nov 1, 1978·Annals of Internal Medicine·W E Stamm
Sep 1, 1987·Archives of Internal Medicine·P CollignonR Munro
Jun 1, 1988·Journal of Clinical Microbiology·F CoutléeJ F Paradis
May 2, 1985·The New England Journal of Medicine·G L Cooper, C C Hopkins
Jun 1, 1985·The Journal of Hospital Infection·E G WilkinsD C Davidson
Sep 1, 1986·The Journal of Hospital Infection·N C Weightman, D C Speller
Jan 1, 1988·Intensive Care Medicine·M L PlitJ Gavaudan
Apr 1, 1988·Journal of Clinical Microbiology·T M HaslettE M Vellozzi
Jan 1, 1988·Intensive Care Medicine·P CollignonP Woods
May 1, 1988·Journal of Clinical Microbiology·A Sitges-Serra, J Liñares
May 1, 1987·Archives of Internal Medicine·C Brun-BuissonM Rapin
Aug 1, 1987·The Pediatric Infectious Disease Journal·P M FlynnF F Barrett
May 15, 1986·The New England Journal of Medicine·P J CollignonP J Garret
Mar 1, 1985·Surgery·A Sitges-SerraJ Garau
Sep 15, 1984·The Medical Journal of Australia·P J CollignonT C Sorrell
Jun 1, 1980·The Journal of Infectious Diseases·D J CleriS J Seligman

❮ Previous
Next ❯

Citations

Feb 19, 1998·Journal of Biomedical Materials Research·K MerrittJ M Anderson
May 1, 1992·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·J A CapdevilaJ M Martínez-Vázquez
Feb 1, 1995·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·E AnaissieI Raad
Sep 1, 1992·Diagnostic Microbiology and Infectious Disease·J GutiérrezE Martín
Sep 30, 2014·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·Zehra IleriDuygu Findik
Dec 1, 1995·Zentralblatt Für Bakteriologie : International Journal of Medical Microbiology·H GoldschmidtW Hunstein
Nov 1, 2006·Acta Anaesthesiologica Scandinavica·M NeuburgerA Borgeat
Nov 3, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H HengartnerM A Grotzer
Feb 1, 1993·The Journal of Hospital Infection·A M KnudsenM W Bentzon
May 26, 2006·Critical Care : the Official Journal of the Critical Care Forum·Leonardo LorenteMaría L Mora
Feb 4, 2010·Annals of Clinical Microbiology and Antimicrobials·Manuel S Rangel-FraustoVictor D Rosenthal
Nov 11, 2005·Critical Care : the Official Journal of the Critical Care Forum·Leonardo LorenteMaría L Mora
Apr 1, 1991·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·S Curtas, K Tramposch
Jul 28, 2009·British Journal of Nursing : BJN·Juan Luis González LópezAna Arribi Vilela
Jun 1, 1990·Journal of Clinical Microbiology
Apr 1, 1997·Journal of Clinical Microbiology·Y Siegman-IgraB M Farr

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Mayo Clinic Proceedings
M L CoronaR L Thompson
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
J RelloJ Puig de la Bellacasa
© 2022 Meta ULC. All rights reserved