Laboratory testing of the insect repellents IR3535 and DEET against Phlebotomus mascittii and P. duboscqi (Diptera: Psychodidae)

International Journal of Medical Microbiology : IJMM
T J NauckeHans-Werner Grünewald

Abstract

The efficacy of the repellent IR3535 was tested and compared with DEET using two laboratory colonies of phlebotomine sand flies, Phlebotomus mascittii and Phlebotomus duboscqi. P. duboscqi, originating from Senegal, is a proven vector of Leishmania major. P. mascittii (Corsican origin) has never been demonstrated to be a vector of leishmaniasis, but it was reported in 2004 as an anthropophilic species in Germany associated with autochthonous visceral leishmaniasis in people and animals. IR3535 and DEET were tested at an effective concentration of 10% in ethanol on two (one male, one female) human volunteers. The mean protection time against P. duboscqi was 5.9h for both repellents, against P. mascittii 10.4 and 8.8 h for IR3535 and DEET, respectively.

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Citations

Dec 17, 2008·Parasitology Research·T J NauckeS Lorentz
Jun 12, 2010·Journal of Travel Medicine·Larry I GoodyerMustapha Debboun
Aug 21, 2010·The Journal of Pharmacy and Pharmacology·Alexander JahnJung Sun Kim
Feb 1, 2019·Molecular Biology Reports·Zeynep IyigundogduFikrettin Sahin
Nov 16, 2019·Journal of Vector Ecology : Journal of the Society for Vector Ecology·Emma N I WeeksSarah Dewhirst

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