PMID: 9437233Jan 23, 1998Paper

Lack of effects of circulating thyroid hormone levels on serum leptin concentrations

European Journal of Endocrinology
S CorbettaP Beck-Peccoz

Abstract

Leptin is the protein product of the ob gene, secreted by adipocytes. It has been suggested that it may play an important role in regulating appetite and energy expenditure. The aim of this study was to evaluate a possible interaction of thyroid hormones with the leptin system. We studied 114 adult patients (65 females and 49 males): 36 were affected with primary hypothyroidism (PH), 38 with central hypothyroidism (CH) and 40 with thyrotoxicosis (TT). Patients with CH were studied both before and after 6 months of L-thyroxine replacement therapy. Body mass index (BMI; kg/m2), thyroid function and fasting serum leptin were assessed in all patients. Since BMI has been proved to be the major influencing variable of circulating leptin levels, data were expressed as standard deviation score (SDS) calculated from 393 male and 561 female controls matched for age and BMI. No difference in SDS was recorded between males and females whatever the levels of circulating thyroid hormones. In males, no significant difference was recorded among the SDSs of PH (-0.36 +/- 1.2), TT (-0.35 +/- 1.2) and CH (0.01 +/- 1.4) patients. Females with PH had an SDSs significantly lower than TT females (-0.77 +/- 1.0 vs -0.06 +/- 1.2; P < 0.02), while no si...Continue Reading

Citations

Feb 7, 2004·Archives of Gerontology and Geriatrics·D MaugeriP Panebianco
Dec 17, 2008·Nutrition Research Reviews·Cibele Aparecida CrispimMarco Túlio de Mello
Dec 4, 2008·International Journal of Obesity : Journal of the International Association for the Study of Obesity·S CamastraE Ferrannini
Apr 10, 1999·Clinical Endocrinology·M Korbonits
Jul 9, 2002·Clinical Endocrinology·Ching-Jung HsiehMing-Chun Kuo
Feb 28, 2001·Diabetes, Obesity & Metabolism·R SimóJ Mesa
Oct 30, 1998·The Proceedings of the Nutrition Society·W F BlumW Rascher
Oct 3, 2000·Thyroid : Official Journal of the American Thyroid Association·N SeraK Eguchi
Jan 27, 1999·Thyroid : Official Journal of the American Thyroid Association·M J DiekmanW M Wiersinga
Jun 12, 1999·Thyroid : Official Journal of the American Thyroid Association·M A SyedL A Burmeister
Sep 1, 2005·Thyroid : Official Journal of the American Thyroid Association·Ronald M Lechan, Csaba Fekete
Jun 5, 2007·Thyroid : Official Journal of the American Thyroid Association·Ulla Feldt-Rasmussen
May 7, 2009·Thyroid : Official Journal of the American Thyroid Association·Patrícia F S TeixeiraMário Vaisman
Sep 1, 2012·Thyroid : Official Journal of the American Thyroid Association·Leonidas H Duntas, Bernadette Biondi
Aug 15, 2000·Annual Review of Nutrition·R B Harris
Nov 18, 2006·International Breastfeeding Journal·Yesim Ozarda IlcolTanju Ozkan
May 8, 2004·Journal of Endocrinological Investigation·F SantiniA Pinchera
Apr 16, 2010·European Journal of Endocrinology·Ferruccio SantiniAldo Pinchera
Jul 26, 2011·Journal of Thyroid Research·Mirella HageSami T Azar
Feb 23, 2013·Biochimica Et Biophysica Acta·Cheng-Yi ChenKwang-Huei Lin
Nov 17, 2007·Cytokine·Pedro Iglesias, Juan J Díez
Sep 17, 2004·Journal of Cellular Biochemistry·Subhashini YaturuSidney R Grimes
Nov 23, 2007·Clinical Endocrinology·Massimiliano RuscicaPaolo Magni
Nov 24, 1999·Frontiers in Neuroendocrinology·F F Casanueva, C Dieguez
Feb 3, 2000·Critical Reviews in Clinical Laboratory Sciences·J Himms-Hagen
Jul 6, 2000·Pediatrics International : Official Journal of the Japan Pediatric Society·T AsamiM Uchiyama
Mar 13, 2001·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·B M Obermayer-PietschT R Pieber
May 27, 2004·European Journal of Clinical Nutrition·P MagniM M Corsi
Dec 17, 1997·The Journal of Clinical Endocrinology and Metabolism·S R BornsteinL Engelmann
Oct 30, 1998·The Proceedings of the Nutrition Society·S W CoppackV Mohamed-Ali
Jun 27, 2001·Journal of Atherosclerosis and Thrombosis·M MatsubaraS Katayose
May 21, 2015·Einstein·Miriane de OliveiraCelia Regina Nogueira
May 10, 2001·The Journal of Clinical Endocrinology and Metabolism·L GhizzoniS Bernasconi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

© 2021 Meta ULC. All rights reserved