PMID: 15368801Sep 17, 2004Paper

Lack of increased left main coronary artery dimensions in hypertensive patients with left ventricular hypertrophy and coronary artery disease. An intracoronary ultrasound study

Acta Cardiologica
Manolis VavuranakisChristodoulos Stefanadis

Abstract

Left main coronary artery dimensions were evaluated in patients with and without arterial hypertension, in the presence of coronary artery disease, and correlated to left ventricular mass. Intracoronary ultrasound was performed in 25 patients (pts) with coronary artery disease and hypertension (+HTN) and in 25 pts with coronary artery disease only (-HTN). Maximal left main dimensions and left ventricular mass index (LVMI) were measured. +HTN pts had greater LVMI compared to -HTN, (+HTN = 183 +/- 17 g/m2 vs. -HTN = 82 +/- 22 g/m2, p < 0.0001), while maximal left main vessel area was similar (25.99 +/- 5.01 mm2 vs. 25.62 +/- 3.3 mm2, p = 0.8). No correlation was found between LVMI and left main vessel area in + HTN. Pts with +HTN despite the increased LVMI do not manifest increased LM dimensions. This may affect mid-term clinical outcome.

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