Lack of production response in grazing dairy cows supplemented with long-acting injectable vitamin B12

New Zealand Veterinary Journal
N D Grace, S O Knowles

Abstract

To determine the concentrations of vitamin B₁₂ in serum, liver and milk that identify adequate vitamin B(12) status in grazing lactating cows, based on no change in milk production in response to supplementation with vitamin B₁₂. In October 2005, in early lactation, Friesian cows from one herd were injected S/C with 60 or 90 mg long-acting vitamin B₁₂, or no injection (Control; n=39 per group, Day 0). Pasture samples were collected for Co determination at monthly intervals over 82 days. Concentrations of vitamin B₁₂ in milk and serum (n=10 per group) and in liver (n=5 per group) were assessed over 124 days. Milk production and composition were determined on four occasions for all cows. Mean concentrations of Co in pasture ranged from 0.11 to 0.34 mg/kg dry matter (DM). Mean initial concentrations of vitamin B₁₂ in milk, serum and liver were 1,520, 128 pmol/L and 1,092 nmol/kg fresh tissue, respectively. Administration of 60 and 90 mg vitamin B₁₂ had similar effects and increased concentrations of vitamin B(12) in milk by 3-fold over controls on Day 50 (7,410 vs. 2,350 pmol/L; p<0.001) and 1.6-fold on Day 124 (3,470 vs. 2,210 pmol/L; p=0.011). Treatment with 60 and 90 mg vitamin B₁₂ increased concentrations of vitamin B₁₂ in ser...Continue Reading

References

Jul 1, 1987·The British Veterinary Journal·A MacPhersonC N Taylor
Oct 1, 1985·Clinical Biochemistry·D S Lee, B W Griffiths
Dec 1, 1970·The British Journal of Nutrition·R M Smith, H R Marston
Mar 1, 1989·New Zealand Veterinary Journal·R G ClarkJ D Rowland
Oct 19, 2005·Journal of Animal Science·M E Tiffany, J W Spears

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.