Lack of radiation optic neuropathy in 72 patients treated for pituitary adenoma

Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
Alfons C M van den BerghJan-Willem R Pott

Abstract

The incidence of radiation optic neuropathy (RON) after external photon beam radiation therapy for nonfunctioning pituitary adenoma (NFA) is not well-studied. Retrospective review of ophthalmological and imaging data in 72 patients with NFA treated between 1985 and 1998 with external beam radiation therapy after surgery Clinical follow-up after radiation therapy had to be at least 18 months. RON was defined as a sudden and profound irreversible visual loss affecting the optic nerve or chiasm A review of previously published cases of RON was then performed. In our cohort, no patient had RON. A total of 11 adequately documented series reports of RON were found in the medical literature on radiation-treated NFAs. The incidence of RON in NFA from these series is 0.53% (95% CI, 0.26%-0.96%). An additional 14 single RON cases have been reported, bringing the total of adequately documented RON cases to 25. RON is a rare complication after external beam radiation therapy for NFA.

References

May 1, 1979·Clinical Endocrinology·A B AtkinsonA R Lyons
Jul 1, 1977·International Journal of Radiation Oncology, Biology, Physics·S AristizabalJ Avila
Feb 1, 1979·Journal of Neurology, Neurosurgery, and Psychiatry·L Symon, J Jakubowski
Nov 1, 1979·International Journal of Radiation Oncology, Biology, Physics·C ErlichmanW J Simpson
Jun 1, 1975·Cancer·D A PistenmaJ R Eltringham
Sep 1, 1977·Journal of Neurosurgery·A N MartinsG Di Chiro
Oct 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·P J Grattan-SmithA O Langlands
Dec 1, 1992·American Journal of Clinical Oncology·D J SalingerC T Miyamoto
Aug 11, 1991·International Journal of Radiation Oncology, Biology, Physics·W M McColloughR R Million
Sep 1, 1991·Clinical Oncology : a Journal of the Royal College of Radiologists·J L MillarJ Delahunt
Feb 1, 1991·American Journal of Clinical Oncology·L M TranR G Parker
Mar 11, 1991·Journal of Neurosurgery·J GuyJ Schiffman
Oct 1, 1990·Journal of Neurosurgery·O al-MeftyR R Smith
Oct 15, 1990·American Journal of Ophthalmology·C F ZimmermanJ S Glaser
Aug 1, 1990·International Journal of Radiation Oncology, Biology, Physics·R J DowsettT A Gennarelli
May 1, 1986·Journal of Neurosurgery·M J EbersoldR V Randall
Aug 1, 1985·Ophthalmology·L B KlineR Ceballos
Mar 1, 1971·Radiology·D H Carlson, S H Marsh
Jan 1, 1971·Radiology·T P HayesA Raventos
Nov 1, 1982·Surgical Neurology·A FukamachiJ Akai
Feb 1, 1995·Neuroradiology·R L McClellanL B Kline
Sep 1, 1994·Clinical Endocrinology·T Mindermann, C B Wilson
Nov 15, 1994·International Journal of Radiation Oncology, Biology, Physics·J T ParsonsR R Million
Dec 1, 1993·International Journal of Radiation Oncology, Biology, Physics·M N HughesL B Tripcony
Oct 6, 1997·International Journal of Radiation Oncology, Biology, Physics·M W McCordW A Friedman
May 14, 1998·Clinical Endocrinology·N J GittoesP M Stewart
Jul 2, 1998·Journal of Endocrinological Investigation·A ColaoG Lombardi
Nov 7, 1998·International Journal of Radiation Oncology, Biology, Physics·M MitsumoriJ S Loeffler
Dec 2, 1998·Journal of Neurosurgery·P BreenA J Martinez
Sep 1, 1999·Clinical Endocrinology·P N Plowman
Jul 13, 2000·International Journal of Radiation Oncology, Biology, Physics·R SasakiY Kuroda
Nov 18, 2000·Journal of Neuro-oncology·K IsobeH Ito
Sep 16, 2003·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Alfons C M van den BerghJan Willem R Pott
Mar 1, 1961·Brain : a Journal of Neurology·M R CROMPTON, D D LAYTON

❮ Previous
Next ❯

Citations

Dec 11, 2007·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Helen V Danesh-Meyer
Mar 24, 2007·International Journal of Radiation Oncology, Biology, Physics·André P van BeekBruce H R Wolffenbuttel
Jun 24, 2006·Neurosurgery Clinics of North America·Dheerendra Prasad
Oct 11, 2005·Trends in Endocrinology and Metabolism : TEM·Neil J L Gittoes
Jun 7, 2005·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Lizette MowattIoanne Anderson
Jul 14, 2017·Seminars in Ophthalmology·Pavle DoroslovačkiMichelle Alonso-Basanta
Jul 27, 2011·Nature Reviews. Clinical Oncology·XiaoShen WangAvraham Eisbruch
Aug 3, 2005·European Journal of Endocrinology·M RixB Brock-Jacobsen
Aug 17, 2018·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Erica L ArcherJonathan D Trobe
Dec 3, 2015·International Ophthalmology Clinics·Chisaroka W Echendu, Larry S Carpenter
Sep 7, 2004·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·James T Parsons
Feb 29, 2020·BMJ Case Reports·Sultan Aldrees, Jonathan A Micieli
Aug 7, 2010·Hormones : International Journal of Endocrinology and Metabolism·Nikiforos BallianGregory A Kaltsas
Jan 28, 2021·European Journal of Ophthalmology·Kaveh Abri AghdamAli Aghajani
Jul 2, 2021·Neuro-ophthalmology·Fabrício Gomes AtaídesJulianna Joanna Carvalho Moraes De Campos Baldin

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.