Lack of relationship between Doppler indices of diastolic function and left ventricular pressure transients in patients with definite diastolic heart failure

American Heart Journal
Gerard P AurigemmaWilliam H Gaasch

Abstract

The purpose of this study was to compare invasive with noninvasive indices of diastolic function in a well-defined group of patients with diastolic dysfunction and a history of diastolic heart failure. Patients with heart failure and a normal left ventricular (LV) ejection fraction comprise a very large portion of the heart failure population and most are thought to have diastolic heart failure. While clinical and Doppler criteria for diastolic dysfunction and diastolic heart failure have been developed, there remains some controversy about the need for invasive cardiac catheterization and/or echo-Doppler evaluation of LV diastolic function. To date, there is no consensus as to the utility of these 2 methods in the diagnosis of diastolic heart failure. Forty-seven patients (mean age 58 +/- 11 years) with a history of congestive heart failure and preserved ejection fraction (> or =50%) by echocardiography underwent a combined hemodynamic/echo-Doppler study. Patients with coronary disease were excluded. Invasive parameters of LV diastolic function (tau, LV diastolic pressures) and Doppler parameters (peak E, peak A, E/A ratio, isovolumic relaxation time, and E deceleration time) were measured using standard techniques. There was ...Continue Reading

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Citations

Sep 18, 2007·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·S HettwerK Werdan
Apr 12, 2012·Current Heart Failure Reports·Umar A Khan, Gerard P Aurigemma
Dec 5, 2013·BMC Nephrology·Morten SchouUNKNOWN EchoCardiography and Heart Outcome Study (ECHOS) investigators
Jul 10, 2010·International Journal of Environmental Research and Public Health·Véronique L Roger
Mar 3, 2007·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Jean-Stéphane DavidPierre-Yves Gueugniaud
Oct 1, 2011·Obesity Research & Clinical Practice·Hidekatsu FukutaGenjiro Kimura
Mar 17, 2006·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·R StüdeliR Hullin
Aug 10, 2006·IEEE Transactions on Medical Imaging·J L Rojo-AlvarezJ C Antoranz
Nov 28, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Ming ChenSheng-lin Liu
Aug 31, 2013·Circulation Research·Véronique L Roger
Jan 20, 2011·Circulation. Cardiovascular Imaging·Raquel YottiFrancisco Fernández-Avilés
Feb 8, 2014·Circulation·Keith MedeirosGerard P Aurigemma
Feb 20, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Matt M Riordan, Sándor J Kovács
Jul 15, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Daniel BurkhoffHiroyuki Suga
Apr 1, 2021·American Journal of Respiratory and Critical Care Medicine·Lindsay M ForbesDavid B Badesch

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