Lack of response inhibition in rats prenatally exposed to alcohol
Offspring of mothers who consumed either 32, 19, 8, or 0% of their daily caloric intake in the form of ethanol during pregnancy were tested for passive avoidance. At 18 days of age, the number of trials to criterion and the within-group variability were direct functions of the amount of ethanol consumed by the mother during pregnancy. At 41--53 days of age, alcohol-treated pups still required more trials to criterion than controls and had faster speeds into the shock compartment on the first trial. When the progeny of mothers consuming either 35, 17, or 0% ethanol-derived calories during pregnancy were compared for conditioned taste aversion to a lithium chloride solution, a linear dose-response function was again evident. Animals in the alcohol-treated groups showed less suppression of drinking than controls. These investigations indicated that the effects of alcohol exposure in utero were manifested in behavioral outcomes involving response inhibition that were not correlated with the more familiar physical symptoms.
Alcohol-induced conditioned taste aversion in rats. Effect of concentration and prior exposure to alcohol
Increased aggressiveness and lower brain serotonin levels in offspring of mice given alcohol during gestation
Effects of prenatal ethanol exposure on avoidance conditioning in high- and low-avoidance rat strains
Effects of ethyl alcohol administration to rat dams during the gestation period on learning behavior and on levels of monoamines and metabolites in rat pup brain after birth
The effects of alcohol induced malnutrition in pregnancy on offspring brain and behavioral development
Effect of prenatal alcohol exposure on consumption of alcohol and alcohol-induced sleep time in mice
Differential behavioral effects of the neuroactive steroid allopregnanolone on neonatal rats prenatally exposed to alcohol
Problem solving following neonatal exposure to cocaine, ethanol, or cocaine/ethanol in combination in rats
Fetal alcohol syndrome and mental retardation: spine distribution of pyramidal cells in prenatal alcohol-exposed rat cerebral cortex; a Golgi study
Prenatal ethanol exposure alters the post-lesion reorganization (sprouting) of acetylcholinesterase staining in the dentate gyrus of adult rats
Effects of alcohol exposure during different periods of development: changes in hippocampal mossy fibers
Impaired spatial navigation in adult female but not adult male rats exposed to alcohol during the brain growth spurt
Age-related changes of the mossy fibre system in rat hippocampus: effect of long term acetyl-L-carnitine treatment
Beneficial effect of chronic nimodipine treatment on behavioral dysfunctions of aged rats exposed to perinatal ethanol treatment
Prenatal ethanol exposure alters immune capacity and noradrenergic synaptic transmission in lymphoid organs of the adult mouse
Acute alcohol exposure during gestational day 8 in the rat: effects upon physical and behavioral parameters
Evidence for altered lesion-induced sprouting in the dentate gyrus of adult rats exposed to ethanol in utero
Effects of scopolamine on spontaneous alternation and shuttle avoidance in rats exposed to alcohol in utero
Prenatal exposure to ethanol decreases the sensitivity of the adult rat hippocampus to N-methyl-D-aspartate
Effects of prenatal alcohol exposure on birth weight in rats: is there an inverted U-shaped function?
Fetal alcohol effects in long- and short-sleep mice: activity, passive avoidance, and in utero ethanol levels
Early gestational exposure to moderate concentrations of ethanol alters adult behaviour in C57BL/6J mice
The impact of prenatal stress, fetal alcohol exposure, or both on development: perspectives from a primate model
Effects of prenatal ethanol exposure and early experience on radial maze performance and conditioned taste aversion in mice
Effects of ethyl alcohol administration to THA rat dams during their gestation period on learning behavior and on levels of monoamines and metabolites in the brain of pups after birth
A review of the neurobehavioral deficits in children with fetal alcohol syndrome or prenatal exposure to alcohol
Prenatal ethanol exposure differentially alters behavior in males and females on the elevated plus maze
Fetal alcohol syndrome: early olfactory learning as a model system to study neurobehavioral deficits
Prenatal alcohol exposure reduces the proportion of newly produced neurons and glia in the dentate gyrus of the hippocampus in female rats
Prenatal alcohol exposure: fetal programming and later life vulnerability to stress, depression and anxiety disorders
Prenatal alcohol exposure: foetal programming, the hypothalamic-pituitary-adrenal axis and sex differences in outcome
Effects of prenatal ethanol exposure on basal limbic-hypothalamic-pituitary-adrenal regulation: role of corticosterone
Computational models of ethanol-induced neurodevelopmental toxicity across species: Implications for risk assessment
Effects of an oil enriched in gamma linolenic acid on locomotor activity and behaviour in the Morris Maze, following in utero ethanol exposure in rats
The neuroteratogenicity of procarbazine in the rat: behavioral, morphological, and neurochemical aspects
gamma-Linolenic acid fails to prevent the effects of prenatal ethanol exposure on brain and behavioral development in B6D2F2 mice
Anterior cingulate cortex surface area relates to behavioral inhibition in adolescents with and without heavy prenatal alcohol exposure
Effects of prenatal ethanol exposure on the hippocampal neurochemistry of albino rats at 90 days of postnatal age
The free radical spin trapping agent phenylbutylnitrone reduces fetal brain DNA oxidation and postnatal cognitive deficits caused by in utero exposure to a non-structurally teratogenic dose of ethanol: a role for oxidative stress
Oxidative DNA damage in the in utero initiation of postnatal neurodevelopmental deficits by normal fetal and ethanol-enhanced oxidative stress in oxoguanine glycosylase 1 knockout mice
A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors
Chronic Gestational Exposure to Ethanol Leads to Enduring Aberrances in Cortical Form and Function in the Medial Prefrontal Cortex
Behavioral deficits induced by third-trimester equivalent alcohol exposure in male C57BL/6J mice are not associated with reduced adult hippocampal neurogenesis but are still rescued with voluntary exercise
Moderate prenatal alcohol exposure impairs cognitive control, but not attention, on a rodent touchscreen continuous performance task.
Chronic prenatal ethanol exposure impairs conditioned responding and enhances GABA release in the hippocampus of the adult guinea pig
Experimental approaches to the investigation of behavioral disorders associated with prenatal alcohol exposure
Effects of prenatal alcohol exposure on neonatal sleep-wake behaviour and adult alcohol consumption in rats
Maternal ethanol consumption and fetal development in the rat: a comparison of ethanol exposure techniques
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