Lactase non-persistence and general patterns of dairy intake in indigenous and mestizo chilean populations

American Journal of Human Biology : the Official Journal of the Human Biology Council
Catalina I FernándezSergio V Flores

Abstract

Lactase persistence (LP) is a genetic trait that has been studied among different countries and ethnic groups. In Latin America, the frequencies of this trait have been shown to vary according to the degree of admixture of the populations. The objective of this study is to better understand the relationship between this genetic trait and dairy intake in a multiethnic context through a synthesis of studies conducted in four regions of Chile. Genotypes frequencies for the SNP LCT-13910C>T (rs4988235) and frequency of dairy consumption were obtained from four populations: Polynesians from Easter Island (Rapanui); Amerindians (Mapuche) and Mestizos from the Araucanía region; urban Mestizos from Santiago; and rural Mestizos from the Coquimbo region. Genetic differentiation and association between milk consumption and genotype frequencies were estimated. Genetic differentiation between Native and Mestizo populations was significant; the LP frequency in Mapuche and Rapanui was 10% and 25%, respectively, whereas among the Mestizos, LP frequency was near 40%. Dairy intake was below the nutritional recommendations for the four groups, and extremely below recommendations among the indigenous populations. Association between milk intake an...Continue Reading

References

Jul 19, 1975·British Medical Journal·G C Cook, M T al-Torki
Jul 14, 1973·Lancet·G Flatz, H W Rotthauwe
Aug 1, 1996·The American Journal of Clinical Nutrition·T H VesaT Sahi
May 1, 1997·The American Journal of Clinical Nutrition·F L SuarezM D Levitt
Apr 12, 2000·Journal of the American College of Nutrition·T H VesaR Korpela
May 15, 2001·Journal of the American College of Nutrition·K A Jackson, D A Savaiano
Sep 19, 2001·Theoretical Population Biology·K Aoki
Jan 15, 2002·Nature Genetics·Nabil Sabri EnattahIrma Järvelä
Sep 5, 2002·American Journal of Physical Anthropology·Michael V OsierKenneth K Kidd
Nov 25, 2003·Nature Genetics·Albano Beja-PereiraGeorg Erhardt
Feb 3, 2004·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Barbara M Obermayer-PietschWilfried Renner
Sep 28, 2004·Journal of Pediatric Gastroenterology and Nutrition·Patrícia Martins Luizari EscobozaLívia Carvalho Galvão
Nov 22, 2005·QJM : Monthly Journal of the Association of Physicians·M GugatschkaB Obermayer-Pietsch
Dec 24, 2005·Journal of the American College of Nutrition·Katherine G Byers, Dennis A Savaiano
Apr 20, 2006·Analytical Biochemistry·Dominique QuinqueIvan Nasidze
Dec 13, 2006·Nature Genetics·Sarah A TishkoffPanos Deloukas
Oct 16, 2007·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·A C BulhõesT R Silveira
Oct 25, 2007·Alimentary Pharmacology & Therapeutics·M C E LomerJ D Sanderson
Jan 23, 2008·PLoS Genetics·Jonathan S FriedlaenderJames L Weber
Feb 11, 2010·BMC Evolutionary Biology·Yuval ItanMark G Thomas
Sep 3, 2010·Nature·UNKNOWN International HapMap 3 ConsortiumJean E McEwen
May 14, 2011·Molecular Ecology Resources·Laurent Excoffier, Heidi E L Lischer
Jan 25, 2012·American Journal of Physical Anthropology·Deise C FriedrichMara H Hutz
Nov 7, 2012·Nature·UNKNOWN 1000 Genomes Project ConsortiumGil A McVean
Sep 3, 2013·American Journal of Human Genetics·Bryony L JonesDallas M Swallow
Aug 7, 2014·Digestion·Gonzalo LatorreJosé Chianale
Aug 20, 2014·American Journal of Physical Anthropology·Catalina I Fernández, Sergio V Flores
Nov 28, 2014·Scientific Reports·C WarinnerM J Collins
Mar 18, 2015·Nature Communications·Susana EyheramendyGabriela M Repetto

❮ Previous
Next ❯

Citations

Sep 29, 2018·Annals of Human Genetics·Nicolás MontalvaDallas M Swallow
May 28, 2020·American Journal of Human Biology : the Official Journal of the Human Biology Council·Morgan K Hoke
Jan 29, 2019·The Journal of Nutrition·Thanh T HoangUNKNOWN National Birth Defects Prevention Study
Oct 12, 2021·Frontiers in Genetics·Ana Cecília Guimarães AlvesVictor Borda

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

American Journal of Physical Anthropology
Catalina I Fernández, Sergio V Flores
American Journal of Human Biology : the Official Journal of the Human Biology Council
Ronald Rodrigues de MouraLucas André Cavalcanti Brandão
American Journal of Human Biology : the Official Journal of the Human Biology Council
L. Pineda BernalL. Borjas-Fajardo
© 2021 Meta ULC. All rights reserved