Lactate compared with pH analysis at fetal scalp blood sampling: a prospective randomised study

British Journal of Obstetrics and Gynaecology
M WestgrenB Persson

Abstract

Fetal scalp blood sampling is a widely used method for assessing fetal condition in the event of ominous fetal heart rate patterns. The purpose of this randomised trial was to compare the value of fetal scalp blood lactate and pH management in cases of abnormal intrapartum fetal heart rate tracings. Of 341 cases of ominous fetal heart rate patterns, 169 were randomly assigned to pH analysis, and 172 to lactate measurements. Lactate was measured using a lactate card requiring 5 microL of blood and yielding the result within 60 seconds. pH analysis was performed with an ABL 510 acid-base analyser requiring 35 microL of blood and yielding the results within 47 seconds. Unsuccessful fetal blood sampling procedures (no result or an unreliable result) occurred significantly more often in the pH subgroup than in the lactate subgroup (OR 16.1 with 95% CI 5.8-44.7). In the pH subgroup the failure rate was inversely related to the degree of cervical dilatation. Compared with the pH subgroup, the lactate subgroup was characterised by fewer fetal scalp incisions per blood sampling attempt (median 1.0 [interquartile range (IQR) 1-1] vs 2.0 [IQR 1-2]), and significantly less time required for the sampling procedure (median 120 s [IQR 90-147]...Continue Reading

References

Jun 15, 1979·American Journal of Obstetrics and Gynecology·A D HaverkampH E Thompson
Apr 1, 1992·British Journal of Obstetrics and Gynaecology·L NordströmM Westgren
Jul 2, 1988·BMJ : British Medical Journal·V J Ruth, K O Raivio
Oct 1, 1989·British Journal of Obstetrics and Gynaecology·A M WhebleG S Sykes
Jan 1, 1987·British Journal of Obstetrics and Gynaecology·P van den BergE Saling
Oct 1, 1983·British Medical Journal·G S SykesA C Turnbull
Jun 1, 1984·American Journal of Obstetrics and Gynecology·R P Perkins
Nov 1, 1995·American Journal of Obstetrics and Gynecology·M WestgrenL Nordström
Mar 1, 1994·Acta Obstetricia Et Gynecologica Scandinavica·L NordströmM Westgren
Jun 1, 1994·Obstetrics and Gynecology·T M GoodwinR H Paul
Nov 1, 1995·British Journal of Obstetrics and Gynaecology·L NordströmM Westgren

❮ Previous
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Citations

Apr 26, 2005·Gynécologie, obstétrique & fertilité·R RamanahJ-P Schaal
Dec 5, 1998·Obstetrics and Gynecology·K KrügerM Westgren
Mar 22, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·L NordströmS Arulkumaran
Apr 3, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·L NordströmS Arulkumaran
May 27, 2008·BMJ : British Medical Journal·James P Neilson
Aug 9, 2008·International Journal of Nanomedicine·Tak S Ching, Patricia Connolly
Aug 10, 2000·Analytical Biochemistry·S D'AuriaJ R Lakowicz
Jan 9, 2008·Journal de gynécologie, obstétrique et biologie de la reproduction·B Carbonne, A Nguyen
Jan 22, 2008·Journal de gynécologie, obstétrique et biologie de la reproduction·O Dupuis, A Simon
May 26, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Christina RørbyeCarsten Nickelsen
Aug 9, 2015·Best Practice & Research. Clinical Obstetrics & Gynaecology·Bruno CarbonneEmeline Maisonneuve
Jul 19, 2012·BJOG : an International Journal of Obstetrics and Gynaecology·M HolzmannL Nordström
Jul 15, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Ayesha M F HeinisFred K Lotgering
Jun 29, 2011·Acta Obstetricia Et Gynecologica Scandinavica·Lena LiljeströmMaria Jonsson
Mar 16, 2011·BJOG : an International Journal of Obstetrics and Gynaecology·A E P HeazellJ E Myers
Jan 30, 2014·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Thea Bowler, Michael Beckmann
Oct 15, 2013·Acta Obstetricia Et Gynecologica Scandinavica·Lena LiljeströmMaria Jonsson
Jun 9, 2004·Best Practice & Research. Clinical Obstetrics & Gynaecology·Lennart Nordström
Dec 10, 1999·Obstetrics and Gynecology Clinics of North America·K R Greene
Oct 5, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Gerard H VisserUNKNOWN FIGO Intrapartum Fetal Monitoring Expert Consensus Panel
Apr 29, 2015·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Tomas Prior, Sailesh Kumar
Nov 16, 1999·American Journal of Obstetrics and Gynecology·K KrugerM Westgren
Nov 21, 2000·American Journal of Obstetrics and Gynecology·J A SpencerP Brocklehurst
Dec 20, 2011·Journal de gynécologie, obstétrique et biologie de la reproduction·A ParisJ Horovitz
Sep 27, 2014·Archives of Gynecology and Obstetrics·Nalan KarabayirElvan Bayramoglu
Dec 9, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Malin HolzmannLennart Nordström
Jun 16, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Malin HolzmannLennart Nordström
Oct 6, 2016·BJOG : an International Journal of Obstetrics and Gynaecology·E R AllansonJ E Dickinson
Dec 22, 1999·Medicine, Conflict, and Survival·T Lindberg
Dec 10, 2016·Acta Obstetricia Et Gynecologica Scandinavica·Ayesha HeinisJoris Van Drongelen
Jun 22, 2011·Obstetrics and Gynecology·Eva Wiberg-ItzelUlla-Britt Wennerholm
May 26, 2018·Acta Obstetricia Et Gynecologica Scandinavica·Ke LuLennart Nordstrom
Feb 7, 2001·The Australian & New Zealand Journal of Obstetrics & Gynaecology·C E Pennell, M B Tracy
Jan 6, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·L IorizzoN Wiberg
Mar 8, 2006·Journal of Perinatal Medicine·Nadav Schwartz, Bruce K Young
Jul 27, 2011·Journal of Perinatal Medicine·Malin HolzmannLennart Nordstrom
Mar 27, 2015·Clinical Obstetrics and Gynecology·Alison G Cahill, Janine Spain
Feb 24, 2001·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·B BauderH Weissenböck
Oct 30, 1998·Obstetrical & Gynecological Survey·L Nordström, S Arulkumaran
Oct 6, 2006·Current Opinion in Anaesthesiology·Marc Van de VeldeMyriam Hanssens
May 17, 2000·Current Opinion in Obstetrics & Gynecology·O A Jibodu, S Arulkumaran

❮ Previous
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