Lactic acid production from xylose by the fungus Rhizopus oryzae

Applied Microbiology and Biotechnology
Ronald H W MaasRuud A Weusthuis

Abstract

Lignocellulosic biomass is considered nowadays to be an economically attractive carbohydrate feedstock for large-scale fermentation of bulk chemicals such as lactic acid. The filamentous fungus Rhizopus oryzae is able to grow in mineral medium with glucose as sole carbon source and to produce optically pure L(+)-lactic acid. Less is known about the conversion by R. oryzae of pentose sugars such as xylose, which is abundantly present in lignocellulosic hydrolysates. This paper describes the conversion of xylose in synthetic media into lactic acid by ten R. oryzae strains resulting in yields between 0.41 and 0.71 g g(-1). By-products were fungal biomass, xylitol, glycerol, ethanol and carbon dioxide. The growth of R. oryzae CBS 112.07 in media with initial xylose concentrations above 40 g l(-1) showed inhibition of substrate consumption and lactic acid production rates. In case of mixed substrates, diauxic growth was observed where consumption of glucose and xylose occurred subsequently. Sugar consumption rate and lactic acid production rate were significantly higher during glucose consumption phase compared to xylose consumption phase. Available xylose (10.3 g l(-1)) and glucose (19.2 g l(-1)) present in a mild-temperature alkal...Continue Reading

References

Feb 1, 1997·Fungal Genetics and Biology : FG & B·A LongacreB E Wright
Jun 1, 2000·Applied and Environmental Microbiology·C D Skory
Jan 5, 2002·Applied Microbiology and Biotechnology·M Carlsen, J Nielsen
Mar 6, 2003·Bioresource Technology·Mohammad J TaherzadehLars Edebo
Aug 12, 2004·Applied Biochemistry and Biotechnology·Y ZhouG T Tsao
Dec 1, 1984·Applied and Environmental Microbiology·R D Medwid, D W Grant
Aug 5, 1997·Biotechnology and Bioengineering·Y KosakaiM Okabe

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Citations

Oct 18, 2007·Journal of Industrial Microbiology & Biotechnology·Siqing LiuTimothy D Leathers
Feb 6, 2008·Journal of Industrial Microbiology & Biotechnology·Ronald H W MaasRuud A Weusthuis
Jun 18, 2010·Journal of Industrial Microbiology & Biotechnology·Yang GuoXinlei Wang
Nov 26, 2009·Applied Biochemistry and Biotechnology·Wei GuoShulin Chen
Dec 23, 2009·Biotechnology for Biofuels·A Maarten J KootstraJohan Pm Sanders
Oct 8, 2009·Bioscience, Biotechnology, and Biochemistry·Ryoji MizunoSatoshi Kaneko
Apr 30, 2013·Biotechnology Advances·Mohamed Ali Abdel-RahmanKenji Sonomoto
Apr 25, 2012·Applied Microbiology and Biotechnology·Bas J MeussenRuud A Weusthuis
Dec 15, 2015·Bioprocess and Biosystems Engineering·Hasan Bugra Coban, Ali Demirci
Sep 4, 2012·Journal of Bioscience and Bioengineering·Tsuneo Yamane, Ryohsuke Tanaka
May 15, 2012·Journal of Bioscience and Bioengineering·Katsuichi SaitoHideyuki Abe
Jan 15, 2008·Trends in Biotechnology·Michael SauerPaola Branduardi
May 10, 2013·Biotechnology Progress·Tsuneo Yamane, Ryosuke Tanaka
Jun 5, 2014·Microbial Biotechnology·Mohan Raj SubramanianLew P Christopher
Feb 25, 2015·Journal of Basic Microbiology·Min ZhangXue-feng Wu
Jun 6, 2015·Applied Microbiology and Biotechnology·Timothy L TurnerYong-Su Jin
Jan 16, 2010·Journal of Chromatography. a·Heidi TurkiaMerja Penttilä
Sep 1, 2018·Brazilian Journal of Microbiology : [publication of the Brazilian Society for Microbiology]·Thalisa Yuwa-Amornpitak, Kannika Chookietwatana
Jul 11, 2019·The Cochrane Database of Systematic Reviews·Malgorzata M BalaJos Kleijnen
Aug 26, 2017·Applied Biochemistry and Biotechnology·Ting JiangJia Ouyang
Jun 30, 2018·Biotechnology Letters·Yixing ZhangPraveen V Vadlani
Oct 28, 2017·Biotechnology for Biofuels·Stefan DörsamKatrin Ochsenreither
Oct 23, 2020·Heliyon·Elahe Abedi, Seyed Mohammad Bagher Hashemi

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