Lactobacillus plantarum PFM 105 Promotes Intestinal Development Through Modulation of Gut Microbiota in Weaning Piglets

Frontiers in Microbiology
Tianwei WangJin Zhong

Abstract

Lactobacillus plantarum is a widespread bacterial species and is commonly used as a probiotic. L. plantarum PFM105 was isolated from the rectum of a healthy sow. Here we found that L. plantarum PFM105 showed probiotic effect on weaning piglets in which intestinal inflammation and unbalanced gut microbiota happened frequently. L. plantarum PFM105 was identified to improve the growth of weaning piglet and promote the development of small intestinal villi. Antibiotics are often used in weaning piglet to prevent intestinal infection and promote the growth of animal. We found that weaning piglets feeding with L. plantarum PFM105 showed similar growth promotion but decreased diarrhea incidence compared with those feeding with antibiotics. High-throughput sequencing was used to analyze the gut microbiota in weaning piglets treated with L. plantarum PFM105 or antibiotics. The relative abundance of beneficial microbes Prevotellaceae and Bifidobacteriaceae were increased in colon of weaning piglet feeding L. plantarum PFM105, while antibiotics increased the relative abundance of bacteria associated with pathogenicity, such as Spirochaeta and Campylobacteraceae. L. plantarum PFM 105 increased indicators of intestinal health including seru...Continue Reading

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Citations

Jul 28, 2020·Animals : an Open Access Journal From MDPI·César BetancurGuillermo Tellez-Isaias
Aug 14, 2019·International Journal of Molecular Sciences·Ghalia KhoderSherif M Karam
Feb 7, 2021·Microorganisms·Paolo TrevisiPaolo Bosi

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Methods Mentioned

BETA
PCR
enzyme-linked immunosorbent assay
ELISA
PCA

Software Mentioned

UPARSE
QIIME
Image
UCHIME
pheatmap
Pro Plus
FLASH
SPSS
PICRUSt
Prism

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