Lactobacillus reuteri modulates cytokines production in exhaled breath condensate of children with atopic dermatitis

Journal of Pediatric Gastroenterology and Nutrition
Vito Leonardo MinielloRuggiero Francavilla

Abstract

We measured the concentration of interferon-gamma and interleukin-4 in the exhaled breath condensate of children with atopic and nonallergic dermatitis receiving a probiotic supplementation (Lactobacillus reuteri ATCC 55730) or placebo for 8 weeks. We demonstrated that the levels of these cytokines increased and decreased respectively only in atopic subjects receiving active treatment. Our data suggest that the oral administration of a specific probiotic strain in patients with atopic dermatitis can modulate in vivo the cytokine pattern at a different site from intestine.

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Citations

Feb 11, 2015·Clinica Chimica Acta; International Journal of Clinical Chemistry·Vito Leonardo MinielloRuggiero Francavilla
Mar 27, 2015·Beneficial Microbes·M van den NieuwboerE Claassen
Dec 18, 2015·Microbiome·Andrew J HoisingtonChristopher A Lowry
Jan 28, 2014·Food Science and Technology International = Ciencia Y Tecnología De Los Alimentos Internacional·N BernatA Chiralt
Aug 10, 2017·Nutrients·Lies HulshofJohan Garssen
May 5, 2018·Frontiers in Microbiology·Qinghui MuXin M Luo
Jun 12, 2020·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Carol Stephanie C Tan-LimMarissa M Alejandria
Jul 17, 2014·Food Science and Technology International = Ciencia Y Tecnología De Los Alimentos Internacional·Neus BernatChelo González-Martínez

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Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.