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Lactobacillus rhamnosus GG-induced expression of Leptin in the intestine orchestrates epithelial cell proliferation

Cellular and Molecular Gastroenterology and Hepatology

Dec 25, 2019

Trevor M DarbyR M Jones

Abstract

Identifying the functional elements that mediate efficient gut epithelial growth and homeostasis is essential for understanding intestinal health and disease. Many of these processes involve the Lactobacillus-induced generation of reactive oxygen species (ROS) by NADPH oxidase (Nox1). H...read more

Mentioned in this Paper

Reactive Oxygen Species
In Vivo
JAK2 protein, human
NADPH Oxidase
Intestines
Colon Structure (Body Structure)
Lactobacillus rhamnosus GG
Epithelial Cell Junction
Ingestion
Organoids
2
Paper Details
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Lactobacillus rhamnosus GG-induced expression of Leptin in the intestine orchestrates epithelial cell proliferation

Cellular and Molecular Gastroenterology and Hepatology

Dec 25, 2019

Trevor M DarbyR M Jones

PMID: 31874255

DOI: 10.1016/j.jcmgh.2019.12.004

Abstract

Identifying the functional elements that mediate efficient gut epithelial growth and homeostasis is essential for understanding intestinal health and disease. Many of these processes involve the Lactobacillus-induced generation of reactive oxygen species (ROS) by NADPH oxidase (Nox1). H...read more

Mentioned in this Paper

Reactive Oxygen Species
In Vivo
JAK2 protein, human
NADPH Oxidase
Intestines
Colon Structure (Body Structure)
Lactobacillus rhamnosus GG
Epithelial Cell Junction
Ingestion
Organoids
2

Similar Papers Found In These Feeds

Organoids

Organoids are three-dimensional structures derived from adult or embryonic stem cells, tissues, or tumors, that enable the mimicry of in vivo architecture in tissue culture. Here is the latest research on organoids.

Lactobacilli for Health Applications

Engineered lactobacilli have successfully been tested as delivery vectors in various disease models, including models of colitis and food and mouth disease. Here is the latest research on the application of lactobacilli for health.

Related Papers

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Epithelial adhesion mediated by pilin SpaC is required for Lactobacillus rhamnosus GG-induced cellular responses

Applied and Environmental MicrobiologyJune 15, 2014
C S ArditaAndrew S Neish
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