Lactobacillus Sepsis following a Laparotomy in a Preterm Infant: A Note of Caution

Neonatology
Marcus BrechtChad Andersen

Abstract

Probiotics for preterm infants have been shown to reduce the incidence of necrotising enterocolitis and all-cause mortality in a recent meta-analysis. It has been argued, however, that some of these results may not be applicable to specific subgroups, e.g. infants with a birth weight of <1,000 g. The specific role of probiotics in improving health outcomes in preterm and term infants following intestinal surgery is not well defined. We report a case of a premature infant diagnosed with late-onset sepsis due to Lactobacillus rhamnosus following a laparotomy. We review pertinent published cases. This case highlights the importance of considering preterm infants as being at a higher risk of systemic probiotic infection following intestinal surgery.

Citations

Sep 2, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·S ViswanathanM C Walsh
Nov 12, 2016·Seminars in Perinatology·Mark A Underwood
May 8, 2019·Nature Medicine·Jotham SuezEran Elinav
May 15, 2019·Microorganisms·Franca RossiGiampaolo Colavita
Aug 20, 2019·Acta Paediatrica·Marijn J VermeulenIrwin K M Reiss
Feb 12, 2020·Journal of Pediatric Gastroenterology and Nutrition·Chris H P van den AkkerHania Szajewska
Jun 11, 2020·Expert Review of Anti-infective Therapy·Dianbin LiuYanxia Wei
Dec 24, 2018·Microbial Biotechnology·Shripada C Rao, Sanjay K Patole
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