Laetrile treatment for cancer

The Cochrane Database of Systematic Reviews
Stefania MilazzoK Schmidt

Abstract

Laetrile is an unconventional therapy which has been used illegally for decades by cancer patients who together with some alternative therapists claim its effectiveness as an anti-cancer treatment. It has been often referred to as amygdalin, although the two are not the same. The aim of this review was to assess the alleged anti-cancer effect and the possible harms of Laetrile as a sole or adjunctive therapy in cancer treatment. We searched The Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE (from 1951); EMBASE (from 1980); Allied and Complementary Medicine (AMED), Scirus, CancerLit, CINAHL (all from 1982); CAMbase (from 1998); the MetaRegister; the National Research Register and our own files. No language restrictions were imposed. Randomized clinical trials (RCTs) and non randomized controlled clinical trials (non-RCTs). Two reviewers independently assessed trials for inclusion in the review, assessed study quality and extracted data. No RCTs or non-RCTs were found, so no abstraction of outcome data could be performed in this systematic review The claim that Laetrile has beneficial effects for cancer patients is not supported by data from controlled clinical trials. This systematic review has clearly identif...Continue Reading

Citations

Apr 29, 2015·The Cochrane Database of Systematic Reviews·Stefania Milazzo, Markus Horneber
Nov 16, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Stefania MilazzoEdzard Ernst
Oct 29, 2014·Cancer Prevention Research·Ann M Bode, Zigang Dong

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