Land use mix and five-year mortality in later life: Results from the Cognitive Function and Ageing Study.

Health & Place
Yu-Tzu WuMRC CFAS

Abstract

This study explores the potential modifying effect of age and mediation effect of co-morbidity on the association between land use mix, a measure of neighbourhood walkability, and five-year mortality among the 2424 individuals participating in the year-10 follow-up of the Cognitive Function and Ageing Study in England. Postcodes of participants were mapped onto Lower-layer Super Output Areas, a small area level geographical unit in the UK, and linked to Generalised Land Use data. Cox regression models were fitted to investigate the association. For the younger older age group (75-79 years), the effect of high land use mix on an elevated risk of mortality was mediated by co-morbidity. For older old age groups (80-84, 85+ years), a higher land use mix was directly associated with a 10% lower risk of five-year mortality. The findings suggest differential impacts of land use mix on the health of the younger and older old.

References

Mar 5, 2003·Brain, Behavior, and Immunity·Louise C Hawkley, John T Cacioppo
Sep 2, 2003·American Journal of Public Health·Kevin M Leyden
Aug 11, 2004·The American Journal of Medicine·Joshua J OfmanScott R Weingarten
Jun 16, 2005·Social Science & Medicine·Astier M Almedom
Jun 21, 2005·Journal of Epidemiology and Community Health·Fuzhong LiMark Bosworth
Feb 14, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Claire A ZizzaCatherine M Wernette
Aug 22, 2009·Maturitas·Philippa Clarke, Els R Nieuwenhuijsen
Apr 1, 2010·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Jane FlemingUNKNOWN Cambridge City Over-75s Cohort (CC75C) Study Collaboration
Sep 3, 2010·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Dick SaarloosOsvaldo P Almeida
Jul 13, 2011·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Verena H MenecJacquie Eales
Jul 19, 2011·Journal of Aging Research·Andrea L RossoYvonne L Michael
Sep 20, 2011·Australasian Journal on Ageing·Duncan BoldyElissa Burton
May 15, 2013·American Journal of Epidemiology·Andrea L RossoYvonne L Michael
Jun 28, 2014·International Journal of Public Health·Ivana KulhánováJohan P Mackenbach

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Citations

Jun 6, 2018·International Journal of Geriatric Psychiatry·Gindo TampubolonNeil Pendleton
Jan 12, 2021·Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition·Rebecca J HirstAnnalisa Setti
Mar 7, 2021·International Journal of Environmental Research and Public Health·Eun Young LeeBo Youl Choi
Aug 5, 2021·Epidemiology·Sandra India-AldanaYu Chen

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