Apr 5, 2020

A snapshot of SARS-CoV-2 genome availability up to 30th March, 2020 and its implications

BioRxiv : the Preprint Server for Biology
Carla MavianM. Salemi


The SARS-CoV-2 pandemic has been growing exponentially, affecting nearly 900 thousand people and causing enormous distress to economies and societies worldwide. A plethora of analyses based on viral sequences has already been published, in scientific journals as well as through non-peer reviewed channels, to investigate SARS-CoV-2 genetic heterogeneity and spatiotemporal dissemination. We examined full genome sequences currently available to assess the presence of sufficient information for reliable phylogenetic and phylogeographic studies in countries with the highest toll of confirmed cases. Although number of-available full-genomes is growing daily, and the full dataset contains sufficient phylogenetic information that would allow reliable inference of phylogenetic relationships, country-specific SARS-CoV-2 datasets still present severe limitations. Studies assessing within country spread or transmission clusters should be considered preliminary at best, or hypothesis generating. Hence the need for continuing concerted efforts to increase number and quality of the sequences required for robust tracing of the epidemic.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Post-Translational Protein Processing
Objective (Goal)
Genetic Translation Process
Gene Circuits
Manipulating Function
Protein Modification Process

Related Feeds

BioRxiv & MedRxiv Preprints

BioRxiv and MedRxiv are the preprint servers for biology and health sciences respectively, operated by Cold Spring Harbor Laboratory. Here are the latest preprint articles (which are not peer-reviewed) from BioRxiv and MedRxiv.

Related Papers

MedRxiv : the Preprint Server for Health Sciences
C. MavianMarco Salemi
American Journal of Clinical Pathology
Ahmed BabikerJeannette Guarner
The New England Journal of Medicine
Xiaoxia LuChinese Pediatric Novel Coronavirus Study Team
Journal of Medical Virology
Beuy Joob, Viroj Wiwanitkit
Journal of Korean Medical Science
Wan Beom ParkMyoung Don Oh
© 2020 Meta ULC. All rights reserved