Langerhans cell histiocytosis: Skin diseases and visceral lesions

Terapevticheskiĭ arkhiv
V D ElkinE V Plotnikova

Abstract

Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder that belongs to class I histiocytoses and is characterized by infiltration of one or many organs by Langerhans cells to form granulomas. The literature analysis could identify a lot of etiological, pathogenetic, and trigger factors and mechanisms for LCH development, which determine the diversity of the clinical picture and course of the disease. The clinical manifestations of LCH are very variable and depend on the severity of lesions and the age of patients. In addition to skin lesions, there is involvement of one or more visceral organs. Difficulties in diagnosing the disease lead to statistical variations of LCH in different countries of the world and require more attention by physicians of all specialties.

References

Sep 1, 1986·Archives of Dermatology·A TaïebJ Maleville
Jan 1, 1995·Critical Reviews in Oncology/hematology·R M Egeler, M E Nesbit
Jul 1, 1994·Clinical and Experimental Dermatology·C R HigginsI M Leigh
Oct 1, 1993·The American Journal of Surgical Pathology·W D TravisR G Crystal
Jan 1, 1996·American Journal of Respiratory and Critical Care Medicine·R S CrausmanT E King
Jan 5, 2002·American Journal of Hematology·A RajS Bertolone
Feb 14, 2002·British Journal of Haematology·Arty Coppes-Zantinga, R Maarten Egeler
Sep 5, 2002·The Journal of Bone and Joint Surgery. British Volume·F PlasschaertB A Alman
Oct 15, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·M AricòC Danesino
Nov 20, 2003·Ophthalmic Plastic and Reconstructive Surgery·Kyung In Woo, Gerald J Harris
Apr 2, 2004·Dermatology : International Journal for Clinical and Investigative Dermatology·Ching-Yuang HuangJulia Yu-Yun Lee
May 15, 2004·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Gerald F AbbottJeffrey R Galvin
Apr 16, 2005·Journal of Periodontology·M ManfrediP Vescovi
Nov 9, 2005·Pediatric Blood & Cancer·Isaac OdameSheila Weitzman
Jan 31, 2006·Journal of the European Academy of Dermatology and Venereology : JEADV·J E GachV A Hill
Nov 30, 2006·Pediatric Hematology and Oncology·Zahra AshenaPeyman Eshghi
Jun 16, 2007·AJNR. American Journal of Neuroradiology·H ProschD Prayer
Mar 21, 2008·Journal of Neurosurgery. Pediatrics·Laurence DavidsonMark D Krieger
Apr 24, 2008·Pediatric Dermatology·Javier MataixCristina Moscardó-Guilleme
Jun 26, 2008·Pediatric Dermatology·Elizabeth K Satter, Whitney A High
Jul 24, 2008·AJR. American Journal of Roentgenology·Nicholas D'AmbrosioSasan Karimi
Sep 23, 2008·The American Journal of Dermatopathology·Tomomi L BillingsSenait Dyson
Jan 28, 2009·Indian Journal of Dermatology, Venereology and Leprology·Kaliyadan FerozeN V Seethalekshmy
Mar 25, 2009·Cancer Investigation·Mahmoud Rezk A Hussein
Oct 24, 2009·Anais Brasileiros De Dermatologia·Leonardo Mello FerreiraIsabella Redighieri
Jan 12, 2010·Cases Journal·Panagiotis V KitsoulisAikaterini Marini
Nov 19, 2010·QJM : Monthly Journal of the Association of Physicians·B Ng-Cheng-HinJ Waxman
Apr 13, 2011·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Cornelia S L MüllerClaudia Pföhler
Aug 3, 2011·The Journal of Dermatology·Ping WangZhaoming Wang
Mar 21, 2012·Orphanet Journal of Rare Diseases·Harpreet S SuriRobert Vassallo
Apr 4, 2012·Indian Journal of Dermatology·Anubhav Garg, Pramod Kumar
Jul 31, 2012·Journal of Cancer Research and Therapeutics·Mohammad A HashmiSuparna Guha
Aug 22, 2012·Annual Review of Pathology·Gayane Badalian-VeryBarrett J Rollins

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