PMID: 6162869Feb 1, 1981

Langerhans cells in dermoid cysts: transmission electron microscopic, cytochemical and immunofluorescent observations

Journal of Cutaneous Pathology
K H ShahG Rowden


Langerhans cells were detected in squamous, stratified epithelia lining human dermoid cysts. Their presence was assayed by ATPase staining and reactivity with heteroantisera against "Ia-like" antigens. Transmission electron microscopic studies demonstrated variations in the numbers of cells showing Birbeck granules in epithelia with different degrees of keratinization. Indeterminate cells (i.e. lacking granules), were more frequent in epithelia showing combined mucous and keratinizing differentiation. Membrane-coating-granules and keratohyalin granules were present in epithelia containing Langerhans cells with clearly identifiable Birbeck granules. Interepithelial mast cells were observed in epithelia with mucous differentiation. A relationship between Langerhans cells and keratinization was suggested. Such non-immune functions are compatible with the known macrophage characteristics of the cell.


Jul 1, 1975·The Journal of Investigative Dermatology·I C Mackenzie
Jan 1, 1979·Canadian Journal of Biochemistry·A K SullivanC Sylvester
Jan 1, 1976·Annals of the New York Academy of Sciences·F BassetJ Turiaf
Jul 21, 1977·Nature·G RowdenA K Sullivan
Jul 21, 1977·Nature·L KlareskogP A Peterson
Jan 1, 1979·International Review of Cytology·A F Hayward
Nov 1, 1979·Nature·J G FrelingerJ A Frelinger
Jan 1, 1976·Annals of the New York Academy of Sciences·R van Furth
Jul 21, 1977·Nature·G StinglK Wolff
Jan 13, 1976·Differentiation; Research in Biological Diversity·C S Potten, T D Allen
Feb 27, 1974·Zeitschrift für Zellforschung und mikroskopische Anatomie·P Böck
Mar 1, 1967·Archives of Oral Biology·J P Waterhouse, C A Squier
Jan 1, 1966·Journal of Periodontal Research·H E Schroeder, J Theilade
Jun 1, 1967·The Journal of Investigative Dermatology·K Wolff, R K Winkelmann
Jan 1, 1974·Virchows Archiv. A, Pathological Anatomy and Histology·F BassetA S Breathnach
May 1, 1973·Journal of Ultrastructure Research·R T Gemmell
Dec 1, 1973·American Journal of Clinical Pathology·M L VernonJ L Sever
Jan 1, 1969·Zeitschrift für Zellforschung und mikroskopische Anatomie·Y Kondo
Feb 1, 1967·Archives of Oral Biology·D S Barker
Oct 12, 1968·Nature·W S Bullough, E B Laurence
Jan 1, 1969·Zeitschrift für Zellforschung und mikroskopische Anatomie·U J Van Haelst
May 15, 1969·Klinische Wochenschrift·M Rupec, S Uhlarik
Jul 1, 1970·Annals of Human Genetics·D Linder, J Power
Jan 1, 1971·The Journal of Investigative Dermatology·Y C Wong, R C Buck
Feb 1, 1968·The Journal of Investigative Dermatology·R J LessardR K Winkelmann
Apr 1, 1968·The British Journal of Dermatology·L B Fisher, G C Wells
Jun 1, 1968·Archives of Dermatology·L Giacometti, B Chiarelli
Mar 1, 1968·Journal of Ultrastructure Research·M HackemannK R Hill
Oct 1, 1968·American Journal of Obstetrics and Gynecology·M S YounesS A Bencosme
Apr 1, 1968·The Journal of Pathology and Bacteriology·M G Lewis
Dec 1, 1968·Archives of Dermatology·A S Zelickson, J H Mottaz
Oct 1, 1965·The Journal of Investigative Dermatology·G D Weinstein, E J Van Scott
Aug 15, 1966·American Journal of Obstetrics and Gynecology·M Thiery, R G Willighagen
Oct 1, 1955·Oral Surgery, Oral Medicine, and Oral Pathology·F A CARRANZA, R L CABRINI
Jan 1, 1964·The American Journal of Anatomy·M A LISTGARTEN


Jan 1, 1985·Journal of Periodontology·C F DiFrancoE Connelly

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